KR-102964253-B1 - RECONSTITUTION DEVICE, SYSTEM, AND METHOD TO ADMINISTER A DRUG IN A MODERATE BOLUS

Abstract

A reconstruction device comprises: a perforating member (30) having a first end (32) and a second end (34), wherein the first end of the perforating member is configured to be coupled to a drug delivery port; a delivery member (40) having a first end (42) and a second end (44), wherein the first end of the delivery member is configured to be coupled to a delivery location; a collar (20) configured to be coupled to a bottle (25); and a cap (22) extending from the collar (20) and holding the perforating member (30) and the delivery member (40) such that the second end (34) of the perforating member and the second end (44) of the delivery member are disposed within a cylindrical collar (20).

Inventors

• 데스브로쎄스 프레디
• 파듈라 피에르파올로
• 만타 버길 클라우디우
• 챔페인 발렌틴

Assignees

• 백스터 인터내셔널 인코포레이티드
• 박스터 헬쓰케어 에스에이

Dates

Publication Date

20260513

Application Date

20180810

Priority Date

20170810

Claims (20)

1. It is a reconstruction device and: A perforating member having a first end and a second end, wherein the first end of the perforating member is configured to be coupled to a drug delivery port; A transmission member having a first end and a second end, wherein the first end of the transmission member is configured to be coupled to a transmission location; A collar configured to be combined with a bottle; and A cap extending from the collar and holding the perforating member and the transfer member such that the second end of the perforating member and the second end of the transfer member are disposed within the collar. Includes, A reconstruction device in which a perforating member extends through a cap to form a first half and a second half of the perforating member, the first half of the perforating member extends from the upper surface of the cap to form a first end of the perforating member, and the second half of the perforating member extends from the lower surface of the cap to form a second end of the perforating member.
2. In paragraph 1, A reconfiguration device in which the cap is formed integrally with the collar.
3. In paragraph 1, A reconfiguration device in which the collar is cylindrical and configured to be concentrically coupled with the bottle.
4. In paragraph 1, A reconfiguration device in which a collar is coupled to a bottle so that a perforating member is in fluid communication with the bottle and a conveying member is in fluid communication with the bottle.
5. In paragraph 1, A reconstructive device in which the administration port is an intravenous ("IV") back port and the first end of the perforation member is configured to perforate the IV back port.
6. In paragraph 1, A reconfiguration device in which the delivery location is an IV line that can be connected to a patient, and the first end of the delivery member is configured to be connected to the IV line.
7. In paragraph 1, A reconfiguration device in which, when placed in an operating position, each of the drilling member and the transmission member is oriented vertically.
8. In paragraph 1, A reconstruction device in which the first end of a perforation member is formed integrally with a drug delivery port.
9. In paragraph 8, A reconfiguration device in which a medication port is connected to an IV solution container.
10. In paragraph 1, A reconstruction device comprising at least one of a first end of a perforating member, a second end of a perforating member, and a second end of a delivery member, comprising a syringe needle.
11. It is a reconstruction system and: Drug bottle; Fluid container; and Reconstruction device Includes, The reconstruction device is: A perforating member having a first end and a second end, wherein the first end of the perforating member is configured to be coupled to a fluid container, A transmission member having a first end and a second end, wherein the first end of the transmission member is configured to be coupled to a transmission location, collar, and A cap extending from the collar and holding the perforating member and the transfer member such that the second end of the perforating member and the second end of the transfer member are disposed within the collar. Includes, A reconstruction system in which a perforating member extends through a cap to form a first half and a second half of the perforating member, the first half of the perforating member extends from the upper surface of the cap to form a first end of the perforating member, and the second half of the perforating member extends from the lower surface of the cap to form a second end of the perforating member.
12. In Paragraph 11, A reconfiguration system in which a collar is coupled to a bottle so that a perforating member is in fluid communication with the bottle and a conveying member is in fluid communication with the bottle.
13. In Paragraph 12, A reconfiguration system in which a fluid container holds a fluid, and accordingly, the fluid can be moved from the fluid container into the first end of a perforating member, through the perforating member, from the second end of the perforating member into a bottle, from the bottle into the second end of a delivery member, through the delivery member, and from the first end of the delivery member to a delivery location.
14. In Paragraph 11, A reconstitution system containing a activator.
15. In Paragraph 14, A reconstitution system in which the active agent is a medicinal product or nutritional supplement.
16. In Paragraph 11, A reconfiguration system in which the fluid container is an IV bag and the delivery location is an IV line that can be connected to a patient.
17. In Paragraph 16, A reconfiguration system further comprising an infusion pump operably connected to an IV line.
18. In Paragraph 11, A reconfiguration system in which a fluid container is formed integrally with a reconfiguration device.
19. This is a method of using the reconstruction system: A step of providing a collar, wherein the collar is combined with a bottle and includes a cap extending from the collar, the cap retains a perforated member having a first end and a second end, the perforated member extends through the cap to form a first half and a second half of the perforated member, the first half of the perforated member extends from the upper surface of the cap to form a first end of the perforated member, and the second half of the perforated member extends from the lower surface of the cap to form a second end of the perforated member; A step of arranging a perforating member and a transmission member so as to be in communication with the inside of the bottle simultaneously; A step of introducing a fluid from a container into a bottle through a first end of a perforating member and through a second end of a perforating member so as to be mixed with an agent located inside the bottle to form a mixed drug; and A step of delivering a mixed drug from a bottle together with fluid from a container through a delivery member. A method including
20. In Paragraph 19, A method comprising the step of delivering a mixed drug from a bottle through a delivery member, the step of connecting the distal end of the delivery member to a tube that can be connected to a patient.

Description

Reconstruction device, system, and method to administer a drug in a suitable bolus Cross-reference regarding related applications The present application claims priority to U.S. Patent Application No. 15/673,813, filed on August 10, 2017, titled "RECONSTITUTION DEVICE, SYSTEM, AND METHOD TO ADMINISTER A DRUG IN A MODERATE BOLUS," the entire contents of which are incorporated herein. Medical treatment often requires the intravenous administration of, for example, fluids to correct electrolyte imbalances, solutions containing medications to deliver drugs, and/or nutrients to provide nutrition to patients for whom oral or enteral nutrition is not possible. Intravenous ("IV") fluids are typically available in sterile single- or multi-chamber flexible containers that include a medication port and a drug port. To enable the administration of fluids to a patient from the flexible container, an IV medication set is typically inserted into the flexible container (e.g., an IV bag) through the medication port. Similarly, medications and/or nutrients may be infused into the flexible container through the drug port. Certain active agents, such as pharmaceuticals and nutrients, that are unstable in liquid form are stored in dry form. For example, active agents may be unstable at the pH of IV fluids, sensitive to light, etc., and accordingly may require storage in dry form. Typically, active agents in dry form may be stored in glass vials sealed with rubber stoppers, or in other containers such as plastic containers, ampoules, or small bags that can be closed with standard screw caps. Before administration to a patient, these active agents in dry form are reconstituted (become liquid again). Reconstitution typically involves removing a protective cover to expose the rubber stopper, wiping the stopper with a sterile cloth, adding a diluent to the vial by inserting the syringe needle through the rubber stopper and placing the contents of the syringe, such as the diluent, into the vial, and shaking the vial to completely dissolve or suspend the active agent. Subsequently, the resulting reconstituted solution or suspension is recovered from the bottle by inserting the syringe needle through the rubber stopper, drawing the solution or suspension into the syringe, and injecting the contents of the syringe into the flexible container through the drug port. However, some drugs and nutrients begin to deteriorate as soon as they are mixed into the flexible container. Ascorbic acid, vitamin B1, and vitamin C, for example, degrade the parenteral nutrition mixture as a whole, while vitamins A and E degrade the parenteral nutrition mixture when exposed to light. Accordingly, an improved system and method utilizing a reconstructing device is required to administer drugs, particularly rapidly degrading drugs. It should be understood that the drawings illustrate only typical embodiments of the present invention and are not to be construed as limiting the scope of the present disclosure, and that the present disclosure is described and explained in detail with additional specificity through the use of the accompanying drawings. The drawings are listed below. FIG. 1 is a perspective view of one embodiment of a reconstructing device according to an exemplary embodiment of the present disclosure. FIG. 2 is an elevation cross-sectional view of the reconstruction device of FIG. 1, further illustrating a fluid flow path according to an exemplary embodiment of the present disclosure. FIG. 3 is a perspective view of one alternative embodiment of a reconfiguration device of the present disclosure, comprising an integrated fluid container. FIG. 4 is a graph regarding the absorption of a reconstituted solution according to the administered volume, as carried out by the reconstitutement device of the present disclosure. FIG. 5 is a schematic diagram of an embodiment of a system using any of the reconfiguration devices described herein. FIG. 6 is an elevation cross-sectional view of an alternative embodiment of a reconfiguration device illustrating an alternative configuration of a flow path according to an exemplary embodiment of the present disclosure. The specific embodiments described herein generally relate to the field of IV administration of activators. More specifically, some embodiments described herein relate to the reconstitution of an activator within a vial and the IV administration of an activator as a suitable bolus using an IV dosing set directly connected to a subsequent vial. As described herein, adding dry medication to an IV bag typically involves several tedious steps. For example, a medical professional may need to remove the protective cover from the bottle, wipe the cap, add a diluent to the bottle, and shake the bottle. Subsequently, the medication must be retrieved from the bottle and administered, for example, into an IV line, IV bag, etc. Furthermore, as previously mentioned, once the medication is reconstituted, it begins t