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KR-102965357-B1 - Feed composition for preventing or improving atopic dermatitis in companion animals, containing bacteriophage and evening primrose oil as active ingredients

KR102965357B1KR 102965357 B1KR102965357 B1KR 102965357B1KR-102965357-B1

Abstract

The objective of the present invention is to provide a feed composition for preventing or improving atopic dermatitis in companion animals, comprising bacteriophages and evening primrose seed oil as active ingredients. It has been confirmed that the mixture of bacteriophages and evening primrose seed oil according to the present invention is excellent for improving atopic dermatitis. Specifically, when the mixture of bacteriophages and evening primrose seed oil was fed to companion animals as a feed composition, it was confirmed that skin lesions on the entire body of the companion animals improved, and that itching and the condition of the skin and coat improved. Therefore, the feed composition for preventing or improving atopic dermatitis in companion animals, comprising bacteriophages and evening primrose seed oil as active ingredients according to the present invention, can be usefully utilized in related businesses.

Inventors

  • 박신후

Assignees

  • 그리츠컴퍼니 주식회사

Dates

Publication Date
20260513
Application Date
20241127

Claims (10)

  1. A feed composition for preventing or improving atopic dermatitis in pets, comprising a mixture of bacteriophage and evening primrose seed oil as an active ingredient.
  2. In Article 1, The above bacteriophage is a feed composition for preventing or improving atopic dermatitis in pets, comprising lysing intestinal microorganisms.
  3. In Paragraph 2, A feed composition for preventing or improving atopic dermatitis in companion animals, comprising one or more of the group consisting of the intestinal microorganisms: Escherichia coli, Aeromonas hydrophila, Bacillus cereus, Lactobacillus sp., Bifidobacterium sp., Clostridium sp., Staphylococcus sp., Acinobacterium sp., Enterococcus faecium, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Enterobacter sp.
  4. In Article 1, The above-mentioned evening primrose seed oil is a double-coated feed composition for preventing or improving atopic dermatitis in pets.
  5. In Article 1, A feed composition for preventing or improving atopic dermatitis in companion animals, comprising a mixture of the above-mentioned bacteriophage and evening primrose seed oil mixed in a weight ratio of 1:100 to 1000.
  6. In Article 1, The above evening primrose seed oil mixture comprises canola oil 38.50 ~ 48.50 wt, microalgae omega 3 oil 0.50 ~ 1.50 wt, coconut oil 0.25 ~ 0.75 wt, evening primrose seed oil 1.50 ~ 2.50 wt, flaxseed powder 0.75 ~ 1.25 wt, fish collagen 2.50 ~ 3.50 wt, Ecklonia cava extract 2.50 ~ 3.50 wt, Coenzyme Q10 0.05 ~ 0.15 wt, hyaluronic acid 0.30 ~ 0.50 wt, taurine 0.75 ~ 1.25 wt, hydrolyzed yeast extract 0.75 ~ 1.25 wt, hydrolyzed chicken 9.00 ~ 11.00 wt, and yucca extract. A feed composition for preventing or improving atopic dermatitis in companion animals, comprising one or more ingredients from the group consisting of 0.10 ~ 0.30 wt, bromelain 0.25 ~ 0.75 wt, Boulardii (yeast) 0.75 ~ 1.25 wt, dextrin 10.00 ~ 13.00 wt, tapioca starch 2.50 ~ 3.50 wt, vitamin E 0.75 ~ 1.25 wt, and proteolytic enzyme 0.25 ~ 0.75 wt.
  7. In Article 1, The above composition is a feed composition for preventing or improving atopic dermatitis in pets, comprising alleviating skin lesions.
  8. In Article 1, The above composition is a feed composition for preventing or improving atopic dermatitis in pets, comprising one or more from the group consisting of Churu, capsule, or powder forms.
  9. A feed additive composition for preventing or improving atopic dermatitis in pets, comprising a mixture of bacteriophage and evening primrose seed oil as an active ingredient.
  10. A food composition for preventing or improving atopic dermatitis in pets, comprising a mixture of bacteriophage and evening primrose seed oil as an active ingredient.

Description

Feed composition for preventing or improving atopic dermatitis in companion animals, containing bacteriophage and evening primrose oil as active ingredients The object of the present invention is to a feed composition for preventing or improving atopic dermatitis in companion animals, comprising bacteriophages and evening primrose seed oil as active ingredients. Specifically, the invention relates to a feed composition and health supplement for companion animals composed of a complex mixture of bacteriophages, which are natural antibiotics, and evening primrose seed oil, which has anti-inflammatory and skin barrier strengthening effects. After bacteriophages penetrate a host and complete the replication process, they express a group of enzymes necessary to break down the cell wall of the host bacterium. These enzymes destroy the cell wall by attacking the murein or peptidoglycan layer of the cell wall, which is responsible for the rigidity and mechanical strength of the cell wall. This is attributed to gamma-linolenic acid (GLA), which is contained in evening primrose seed oil at a concentration of about 7–14%. The above gamma-linolenic acid is an unsaturated fatty acid and serves as the matrix for a physiologically active substance called prostaglandin (PG). Gamma-linolenic acid contained in evening primrose seed oil is widely used globally as an ingredient in health supplements and pharmaceuticals, as it is known to be effective in lowering cholesterol, reducing blood pressure, and preventing adult diseases. However, the fatty acids in evening primrose seed oil contain cis-type unsaturated fatty acids, so they easily undergo oxidation by light or heat, and thus denaturation due to changes in composition, oxidation, and the formation of lipid peroxides acts as a limiting factor in production and storage. Due to demographic changes resulting from an aging population and a surge in single-person households, as well as increased income, the number of households owning pets is on the rise and is evolving from mere pets to life companions. Reflecting this trend, the size of the domestic pet-related market is projected to reach 9 trillion won in 2012, 1.8 trillion won in 2015, and 5.8 trillion won in 2020, indicating that steady market growth is expected in the future. Despite the market's growth trend, foreign brands currently account for over 70% of the pet food market. Consequently, there is a need for measures to improve the low trust in domestic products, identify consumer needs in advance, reduce dependence on imports, and increase the market share of domestic products. Atopy is a chronic, recurrent inflammatory skin disease caused by factors such as rapid environmental changes, genetic factors, immunological abnormalities, and abnormalities in the skin's protective barrier. As the incidence of atopic dermatitis is increasing not only in humans but also in companion animals, interest in treatments to alleviate the condition is growing. Figure 1a is a figure confirming the skin lesion reduction effect of the complex of bacteriophage and evening primrose seed oil mixture of the present invention. Figure 1b is a figure showing the left side of a pet, confirming the skin lesion reduction effect of the complex of bacteriophage and evening primrose seed oil mixture of the present invention. FIG. 1c is a diagram showing the dorsal side of a pet, which confirms the skin lesion reduction effect of the complex of the bacteriophage and evening primrose seed oil mixture of the present invention. Figure 1d is a figure showing the ventral thorax and limbs of a pet showing the skin lesion reduction effect of the complex of the bacteriophage and evening primrose seed oil mixture of the present invention. FIG. 1e is a figure showing the ventral thorax and abdomen of a pet, confirming the skin lesion reduction effect of the complex of the bacteriophage and evening primrose seed oil mixture of the present invention. Fig. 1f is a diagram showing the ventral abdomen and groin of a pet, confirming the skin lesion reduction effect of the complex of the bacteriophage and evening primrose seed oil mixture of the present invention. Figure 2 is a figure confirming the itching-reducing effect of the complex of bacteriophage and evening primrose seed oil mixture of the present invention. Figure 3 is a figure confirming the skin-soothing effect of the complex of bacteriophage and evening primrose seed oil mixture of the present invention. Figure 4 is a figure confirming the effect of the compound of bacteriophage and evening primrose seed oil mixture of the present invention on alleviating the condition of the coat. Hereinafter, the present invention will be described in detail with reference to the attached drawings and embodiments thereof. However, the following embodiments are presented as examples of the present invention, and if it is determined that a detailed description of a technology or configuration well known to those skill