KR-20260062416-A - SAMPLE SEPARATOR AND METHOD OF SEPARATING SAMPLE

KR20260062416AKR 20260062416 AKR20260062416 AKR 20260062416AKR-20260062416-A

Abstract

A sample separator and a sample separation method are disclosed. The sample separator of the present invention comprises: a blade extending longitudinally from a first blade side edge and continuing to a second blade side edge; and a base fixer comprising a base fixer body extending longitudinally and coupled to the blade, wherein the blade base edge forming the lower end of the blade extends longitudinally from the lower end of the first blade side edge and continues to the lower end of the second blade side edge and is coupled to the base fixer body, and the upper surface of the base fixer body may be connected to the blade.

Inventors

유영훈

Assignees

(의) 삼성의료재단

Dates

Publication Date: 20260507
Application Date: 20241029

Claims (12)

A blade extending longitudinally from the first blade side edge and continuing to the second blade side edge; and A base fixer comprising a base fixer body that extends in the above longitudinal direction and is coupled to the blade, and The blade base edge forming the lower end of the blade extends in the longitudinal direction from the lower end of the first blade side edge and connects to the lower end of the second blade side edge, and is coupled to the base fixer body. The upper surface of the above base fixer body is connected to the blade, Sample separator.
In paragraph 1, The thickness of the above blade is, Getting smaller as it goes upward from the blade base edge, Sample separator.
In paragraph 1, The above base fixer is, Further comprising a fixer wing extending from the base fixer body in the thickness direction of the blade, Sample separator.
In paragraph 1, The above base fixer is, A first fixer wing extending from the base fixer body in the thickness direction of the blade and adjacent to the first blade side edge; and Further comprising a second fixer wing extending from the base fixer body in the thickness direction of the blade and adjacent to the second blade side edge, Sample separator.
In paragraph 1, At least one blade module each comprising the blade and the base fixer; and A frame module further comprising a frame module coupled to the base fixer above. Sample separator.
In paragraph 5, The above frame module is, A first frame bar and a second frame bar that extend in one direction and face each other; A plurality of first frame couplers formed on the first frame bar; and It includes a plurality of second frame couplers formed on the second frame bar, and The above base fixer is, A first base fixer coupler coupled to one of the plurality of first frame couplers; and A second base fixer coupler coupled to one of the plurality of second frame couplers, Sample separator.
In paragraph 6, The above-mentioned first base fixer coupler is, It protrudes downward from the lower surface of the base fixer body and is adjacent to the first blade side edge, The above-mentioned second base fixer coupler is, Protruding downward from the lower surface of the base fixer body and adjacent to the second blade side edge, Sample separator.
In paragraph 5, The above frame module is, A first frame bar and a second frame bar, each extending in one direction and having inner surfaces facing each other; A plurality of first frame couplers formed concavely on the inner surface of the first frame bar; and It includes a plurality of second frame couplers formed concavely on the inner surface of the second frame bar, and One end of the base fixer body is coupled to one of the plurality of first frame couplers, and The other end of the base fixer body is coupled to one of the plurality of second frame couplers, Sample separator.
It includes at least one blade module and a frame module coupled to the at least one blade module, and The above frame module is, A first frame bar and a second frame bar that extend in one direction and face each other; A plurality of first side frame couplers formed on the first frame bar; and It includes a plurality of second side frame couplers formed on the second frame bar, and Each of the above-mentioned at least one blade module is, A blade extending longitudinally from the first blade side edge and continuing to the second blade side edge; A first side fixer coupler fixed to the first blade side edge and coupled to one of the plurality of first side frame couplers; and A second side fixer coupler coupled to the second blade side edge and coupled to one of the plurality of second side frame couplers, Sample separator.
In Paragraph 9, Each of the above plurality of first side frame couplers is, A sunken shape is formed on the upper and inner surfaces of the first frame bar, and Each of the above plurality of second side frame couplers is, A shape formed by a depression on the upper and inner surfaces of the second frame bar. Sample separator.
Step (S100) in which at least one blade module partitions a sample block in which a wax-like medium forms a shape that encloses a plurality of samples; Step of placing the above sample block into a mold (S200); and A method comprising the step (S300) of heating the above mold Sample separation method (S10).
In Paragraph 11, The above partitioning step (S100) is, Step of setting a partition line on the upper surface of the above sample block (S110); A step of combining at least one blade module to a frame module (S120); and The method includes the step (S130) in which at least one blade module descends from above the partition line and is inserted into the sample block. Sample separation method (S10).

Description

Sample Separator and Method of Separating Sample The present invention relates to a sample separator and a sample separation method. Generally, tissue slides are prepared for the observation of tissue specimens in hospital pathology departments, clinical pathology laboratories, and the like. Tissue slides can be prepared by thinly cutting (i.e., sectioning) a specimen block containing a tissue specimen (hereinafter abbreviated as specimen) to create specimen sections, placing the sections on a slide, and melting a wax-like medium. For example, a specimen block can be prepared by embedding the specimen in a waxy medium such as paraffin or celloidin. For example, a specimen block can be prepared by injecting a waxy medium into the interior of a cassette (or mold) containing the specimen and curing it. Meanwhile, when multiple specimens are embedded in a specimen block, situations requiring re-embedding may occur (e.g., when it is necessary to change the order of multiple specimens or separate them individually). In this case, a sample block containing multiple samples is placed in a mold and the waxy medium is melted, but the samples become mixed as the waxy medium melts. Consequently, the distinction between the samples may become ambiguous. Therefore, when dissolving a specimen block containing multiple embedded specimens for re-embedding, a method is required to distinguish the specimens from one another once the waxy medium has completely dissolved. FIG. 1 is a drawing showing a blade according to one embodiment of the present invention. FIG. 2 is a drawing showing a blade module according to one embodiment of the present invention. Figure 3 is a schematic diagram showing the blade module illustrated in Figure 2 partitioning a sample block. Figure 4 is a drawing showing a frame module including a base frame coupler. Figure 5 is a drawing showing a base fixer coupler added to the blade module shown in Figure 2. Figure 6 is a drawing showing a frame module including a side frame coupler. Figure 7 is a drawing showing a side fixer coupler added to the blade illustrated in Figure 1. Figure 8 is a drawing showing a fixer wing formed on the blade module illustrated in Figure 2. Figure 9 is a schematic diagram showing a blade inserted into a sample block. FIG. 10 is a flowchart illustrating a sample separation method according to one embodiment of the present invention. Hereinafter, embodiments disclosed in this specification will be described in detail with reference to the attached drawings. Identical or similar components regardless of drawing symbols are assigned the same reference number, and redundant descriptions thereof will be omitted. The suffixes "module" and "part" used for components in the following description are assigned or used interchangeably solely for the ease of drafting the specification and do not inherently possess distinct meanings or roles. Furthermore, in describing the embodiments disclosed in this specification, if it is determined that a detailed description of related prior art could obscure the essence of the embodiments disclosed in this specification, such detailed description will be omitted. Additionally, the attached drawings are intended only to facilitate understanding of the embodiments disclosed in this specification; the technical concept disclosed in this specification is not limited by the attached drawings, and it should be understood that they include all modifications, equivalents, and substitutions that fall within the spirit and technical scope of the invention. Terms including ordinal numbers, such as first, second, etc., may be used to describe various components, but said components are not limited by said terms. These terms are used solely for the purpose of distinguishing one component from another. When it is stated that one component is "connected" or "connected" to another component, it should be understood that while it may be directly connected or connected to that other component, there may also be other components in between. On the other hand, when it is stated that one component is "directly connected" or "directly connected" to another component, it should be understood that there are no other components in between. A singular expression includes a plural expression unless the context clearly indicates otherwise. In this application, terms such as “comprising” or “having” are intended to specify the existence of the features, numbers, steps, actions, components, parts, or combinations thereof described in the specification, and should be understood as not precluding the existence or addition of one or more other features, numbers, steps, actions, components, parts, or combinations thereof. In the drawings, the size of components may be exaggerated or reduced for convenience of explanation. For example, the size and thickness of each component shown in the drawings are depicted arbitrarily for convenience of explanation, so the present invention is