KR-20260063048-A - APPARATUS FOR RESEARCH AND MEDICAL EXPERIMENTS COMBICELL

KR20260063048AKR 20260063048 AKR20260063048 AKR 20260063048AKR-20260063048-A

Abstract

A combi-cell for research and medical experiments related to one embodiment of the present invention may include a centrifuge, a main body having a receiving portion equipped with the centrifuge and partitioned from the centrifuge, a stirrer including a first driving portion equipped with the receiving portion and a stirring plate provided to be detachably mounted to the first driving portion, a constant temperature water bath provided to be insertable and detachable from the receiving portion and open toward the inlet of the receiving portion, a temperature controller provided to heat the air within the receiving portion, and a controller provided to individually control the operation of the centrifuge, the stirrer, and the temperature controller.

Inventors

김종빈

Assignees

퓨리셀매니아 주식회사

Dates

Publication Date: 20260507
Application Date: 20241030

Claims (19)

Centrifuge; A main body equipped with the above-mentioned centrifuge and provided with a receiving portion partitioned from the above-mentioned centrifuge; A stirrer comprising a first driving unit mounted on the above-mentioned receiving portion and a stirring plate provided to be detachably mounted on the first driving unit; A constant temperature water bath provided to be insertable and detachable from the above-mentioned receiving portion and open toward the inlet of the above-mentioned receiving portion; A thermostat provided to heat the air within the above-mentioned receiving portion; and A combicell for research and medical experiments comprising a controller configured to individually control the operation of the centrifuge, the stirrer, and the temperature controller.
In Article 1, A combicell for research and medical experiments, characterized in that the above-described constant temperature water bath is configured to accommodate a sample container and is configured to be mounted on the receiving portion in place of the above-described stirring plate.
In Article 1, The above-mentioned receiving portion is provided with a plurality of mounting grooves recessed from the bottom surface, and A combicell for research and medical experiments, characterized in that the plurality of mounting grooves are spaced apart from the first driving unit and spaced apart in the perimeter direction of the bottom surface of the receiving unit.
In Paragraph 3, A combicell for research and medical experiments, wherein a constant temperature water bath has a plurality of box fastening parts arranged to be insertable into the plurality of mounting grooves, and the plurality of box fastening parts are arranged to protrude below the bottom surface of the constant temperature water bath.
In Article 4, The above box fastening part includes a magnet, and A combicell for research and medical experiments, characterized in that the above-described constant temperature water bath is magnetically coupled to the above-described plurality of mounting grooves and is detachably mounted to the above-described receiving portion.
In claim 1, the temperature controller A heating part including a heating wire arranged to generate heat when current is applied, and configured to be mounted in the receiving part such that the heating wire is exposed to a first inner surface extending from the bottom surface of the receiving part; and A research and medical experimental device combicell configured to heat and convect air within a receiving portion, comprising a blower fan spaced apart from the first inner surface of the receiving portion and the upper portion of the bottom surface of the receiving portion on a different surface, and configured to blow air into the internal space of the receiving portion.
In Article 6, A combicell for research and medical experiments, wherein the above-described temperature controller further comprises a sensor mounted on the inner surface of the receiving portion and configured to detect the air temperature within the receiving portion.
In Article 7, A combicell for research and medical experiments, characterized in that the controller controls the operation of the heating unit and the blower fan so that the temperature within the receiving unit maintains a preset temperature based on the temperature measured by the sensor.
In Article 6, A combicell for research and medical experiments, characterized in that a constant temperature water bath is mounted in the receiving portion so as not to come into contact with the heating wire.
In Article 9, The above constant temperature water bath is a combicell, a research and medical experimental device, configured to be mounted in the above receiving portion separately from the stirring plate.
In Article 1, The above stirring plate is a combicell for research and medical experiments comprising a plurality of container mounting parts arranged to allow a sample container to be detachably inserted and a plate fastening part arranged to be detachably connected to the first driving part.
In Article 11, The above-mentioned first driving unit is a combicell, a research and medical experimental device configured to vibrate the stirring plate.
In Article 11, The above-mentioned first driving unit is a combicell, a research and medical experimental device, configured to rotate the stirring plate.
In Article 1, A combicell for research and medical experiments, characterized in that the stirring plate and the constant temperature water bath are provided to be detachably from the main body, and either the stirring plate or the constant temperature water bath is mounted on the main body together with the centrifuge.
In Article 1, A combicell for research and medical experiments, characterized in that the controller has a centrifugation mode, a stirring mode, and a constant temperature mode pre-set, and the centrifuge, the stirrer, and the temperature controller are individually driven according to the selected mode.
In Article 15, A combicell for research and medical experiments, characterized in that the controller stops the operation of the first drive unit of the stirrer in the constant temperature mode and controls the operation of the temperature controller so that the air inside the receiving unit becomes a set temperature while the constant temperature water bath is mounted in the receiving unit.
In Article 15, A combicell for research and medical experiments, wherein the controller further comprises an operating unit for individually operating the centrifugation mode, the stirring mode, and the constant temperature mode, and a display unit provided to display the operating status of the operating unit.
In Article 1, The above main body is equipped with a container organizer on its outer surface, and The above container organizer is a combicell, a research and medical laboratory device provided to support the above sample containers according to their sizes.
In Article 1, The above centrifuge comprises a rotor configured to accommodate a plurality of sample containers and a driving source configured to rotate the rotor, and is a combicell, a research and medical laboratory device configured to centrifuge the components of a sample contained in the sample containers using centrifugal force.

Description

Apparatus for Research and Medical Experiments Combicell The present invention relates to a combicell for research and medical laboratory use, and more specifically, to a combicell for research and medical laboratory use capable of performing centrifugation, stirring, and constant temperature water bath functions. With the recent advancement of biotechnology, various experiments involving the manipulation of cells and genes are underway, such as developing therapeutic agents to treat human diseases by isolating and culturing cells from human or animal sources, or developing cell and gene therapies created by genetically modifying cells. These experiments are generally conducted through the following processes. For example, depending on the experimental purpose, to isolate cells from animal or human-derived materials, these materials may be treated with an enzyme, reacted in a stirrer and a constant temperature water bath for a certain period, and then the cells to be used in the experiment may be isolated using a centrifuge. Cells separated using a centrifuge are transferred to a clean bench, where a washing solution is added, pipetting is performed, and centrifugation is carried out again. This process can be repeated once or several times depending on the experimental purpose. The separated cells can be injected directly into a patient, or, depending on the experimental purpose, cell culture medium is added and the cells are transferred to a CO2 incubator where they can be cultured. The number of cultured cells can be increased to be used immediately for experimental purposes, or they can be modified into various forms of cells through genetic engineering. This series of processes requires many research devices, such as centrifuges, stirrers, constant temperature water baths, sterile benches, and cell culture incubators, and samples are frequently contaminated during the use of these devices. Centrifuges, shakers, and water baths are among the most frequently used pieces of equipment in laboratories and medical institutions, and these devices are used individually or simultaneously in various situations, such as the separation of cells from various types of tissues, genetic manipulation, and the mixing and separation of materials. However, in general, since these centrifuges, stirrers, and constant temperature water baths are configured separately in laboratories and medical institutions and located in distinct places, they take up a significant amount of space. Furthermore, moving them to other locations for use is cumbersome and time-consuming. Furthermore, as these devices are located in different places, various problems arise during their use, such as the inability to use samples due to errors during the mixing process, sample contamination, and sample deterioration caused by transportation time. For example, during the process of treating tissues isolated from human-derived materials with enzymes, reacting them in a stirrer or constant temperature water bath, and then separating the cells using a centrifuge, the cells may become contaminated; additionally, in cell gene manipulation experiments where rapid processing is required, delays in processing time may result in failure to insert genes. Therefore, in order to eliminate various sources of contamination generated during such experimental processes and to reduce errors, there is a need to develop equipment that can minimize the movement of such equipment and the space occupied by it, which is frequently used in laboratories and medical institutions. FIG. 1 is a schematic perspective view of a combicell, a research and medical experimental device according to one embodiment of the present invention. FIG. 2 schematically illustrates the configuration of a combi-cell, a research and medical experimental device according to one embodiment of the present invention. FIG. 3 schematically illustrates a plan view of a combicell, a research and medical experimental device according to one embodiment of the present invention. FIG. 4 is a cross-sectional view of FIG. 3, schematically illustrating the structure of the receiving portion of the main body and the arrangement of the thermostat mounted on the receiving portion. FIG. 5 schematically illustrates a state diagram in which a constant temperature water bath according to one embodiment of the present invention is mounted in the receiving portion of the main body. FIG. 6 schematically illustrates a state in which a stirring plate according to one embodiment of the present invention is mounted in the receiving portion of the main body. Figure 7 schematically illustrates a perspective view of a stirring plate according to another example. Figure 8 schematically illustrates a perspective view of a container organizer. Hereinafter, a combicell, a research and medical experimental device related to an embodiment of the present invention, will be described with reference to the attached drawings. FIG. 1 schemat