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KR-20260063474-A - Composition for cleaning orthodontic appliance and denture containing natural extracts and proteinase

KR20260063474AKR 20260063474 AKR20260063474 AKR 20260063474AKR-20260063474-A

Abstract

The present invention relates to a composition for cleaning oral appliances comprising, as an active ingredient, a complex containing hibiscus extract, cypress extract, yucca extract, flower moss extract, green tea extract, chitosan, and peppermint oil. A complex or composition containing raw materials obtained from such natural products has excellent antibacterial/antifungal effects against oral bacteria and fungi such as Streptococcus mutans , Porphyromonas gingivalis , Candida albicans , and Acinetobacter johnsonii , has efficacy in preventing bad breath/stomatitis, and can prevent tartar from accumulating on oral appliances. Accordingly, by using the composition of the present invention, users of dental braces, temporomandibular joint braces, bruxism prevention devices, dentures, etc., can maintain more hygienic and clean oral care.

Inventors

  • 최현성

Assignees

  • 주식회사 바오메디텍

Dates

Publication Date
20260507
Application Date
20241030

Claims (9)

  1. A composition for cleaning braces and dentures characterized by comprising, as an active ingredient, a complex derived from natural extracts containing raspberry extract, Cordyceps extract, Echinacea extract, Boswellia extract, green tea extract, beta-sitosterol, and peppermint oil.
  2. In paragraph 1, The above-mentioned compound is a composition for cleaning orthodontic appliances and dentures, characterized by having plaque removal efficacy.
  3. In paragraph 1, The above-mentioned complex is a composition for cleaning orthodontic appliances and dentures, characterized by having antibacterial efficacy against Streptococcus mutans, a cavity-causing bacterium in the oral cavity.
  4. In paragraph 1, The above-mentioned complex is a composition for cleaning braces and dentures characterized by having antibacterial efficacy against Porphyromonas gingivalis , a bad breath-causing bacterium.
  5. In paragraph 1, The above-mentioned complex is a composition for cleaning braces and dentures characterized by having antifungal efficacy against Candida albicans, a causative agent of stomatitis.
  6. In paragraph 1, The above-mentioned complex is a composition for cleaning orthodontic appliances and dentures characterized by having antifungal efficacy against Acinetobacter johnsonii, a causative agent of stomatitis.
  7. In paragraph 1, A composition for cleaning orthodontic appliances and dentures, characterized by comprising eucalyptus oil, calendula extract, chamomile extract, papain, protease, bromelain, ethanol, sodium bicarbonate, L-menthol, glycerin, cocamidopropyl betaine, sodium cocoyl glutamate, floxamer 407, hydrogenated castor oil, fragrance, and purified water in the above complex.
  8. In paragraph 1, The above composition is a dental brace and denture cleaning agent composition characterized by preventing the formation of tartar on the exterior of the dental brace and denture.
  9. In paragraph 1, An oral appliance cleaning composition characterized in that the above-mentioned orthodontic appliance is selected from a dental brace, a temporomandibular joint orthodontic appliance, or a removable bruxism prevention device.

Description

Composition for cleaning orthodontic appliance and denture containing natural extracts and proteinase The present invention relates to a composition for cleaning orthodontic appliances and dentures containing a natural product extract and a proteolytic enzyme. The number of people using various oral appliances, such as devices for orthodontics, temporomandibular joint correction, and bruxism prevention, as well as dentures, is increasing. Consequently, the cleaning of these appliances is closely linked to dental health and oral diseases. Therefore, the removal of dental plaque—composed of microorganisms and their byproducts adhering to the surface of these appliances—is crucial. Currently, various physical devices or chemical compositions are primarily available to remove deposits like dental plaque; thus, there is a growing need for natural-type oral appliance cleaners that are easy to use and harmless to the human body. While imported products developed abroad are manufactured in tablet form in the recent market, they are inconvenient to use after every meal, leading consumers to use toothpaste or dish soap as substitutes. Accordingly, the inventors have completed the present invention by confirming that a hygienic oral environment can be maintained by using a composition containing various natural extracts and protein enzymes with excellent antibacterial/deodorizing/cleaning efficacy as a cleaning agent for oral devices such as braces and dentures. Preferred embodiments of the present invention will be described in detail below. However, the present invention is not limited to the embodiments described herein and may be embodied in other forms. Rather, the content introduced herein is provided to fully convey the concept of the present invention to those skilled in the art, so that it may be thorough and complete. <Examples 1 to 3 and Comparative Examples 1 to 3. Preparation of Natural Product-Derived Complexes> The main active ingredients of the orthodontic appliance and denture cleaning agent composition of the present invention, namely raspberry fruit extract, Cordyceps mycelium extract, Echinacea leaf extract, Boswellia resin extract, green tea leaf extract, beta-sitosterol, and peppermint oil, were first mixed as shown in Table 1 below to first verify the efficacy of various antibacterial and bad breath prevention effects. This is also a procedure to select the most effective one as a cleansing agent composition and to verify appropriate mixing conditions or formulation stabilization conditions with the remaining ingredients, such as enzyme-containing eucalyptus oil, calendula flower extract, chamomile flower extract, papain, protease, bromelain, ethanol, sodium bicarbonate, L-menthol, glycerin, cocamidopropyl betaine, sodium cocoyl glutamate, floxamer 407, hydrogenated castor oil, grapefruit seed extract prepared as a fragrance, and purified water. IngredientsExample 1Example 2Example 3　Comparative Example 1Comparative Example 2Comparative Example 3Raspberry extract (g)1.001.001.00　0.003.002.00Cordyceps extract (g)3.002.502.00　1.002.001.50Echinacea extract (g)2.603.002.00　0.002.001.50Boswellia extract (g)4.003.503.00　1.003.001.50Green tea extract (g)2.001.001.50　3.000.003.00Beta-sitosterol (g)0.300.500.50　2.000.001.63Peppermint oil (g)20.1021.5023.00　26.0023.0021.87Subtotal (g)33.0033.0033.00　33.0033.0033.00 Each extract used as a raw material was prepared by adding 10 times its weight of a 70% (v/v) aqueous ethanol solution to a raw material sample (plant, mycelium, resin) and extracting it at 60°C for 8 hours, then concentrating the resulting liquid under reduced pressure and freeze-drying it. Peppermint oil and eucalyptus oil to be used later were purchased as products manufactured as essential oils. Other raw materials, such as excipients and enzymes, were purchased and used as ingredients commonly used in food or mouthwashes. <Formulation Examples 1 to 3 and Comparative Formulation Examples 1 to 5. Preparation of Formulation Compositions> Formulation compositions were prepared as shown in Tables 2 and 3, using the composite components and content of Example 1 as a representative example. To this end, six types of excipients corresponding to each formulation composition were prepared and compared. The compositions in Tables 2 and 3 were prepared to verify the formulation state according to the content of excipients and the presence or absence of ingredients, and Table 4 is a formulation composition prepared using the components and content of the complex of Comparative Example 3, but there are also differences in the excipients. IngredientsFormulation Example 1 Weight of each ingredient (g)Formulation Example 2 Weight of each ingredient (g)Formulation Example 3 Weight of each ingredient (g)Raspberry extractline city yes 1 luck bout water1.00line city yes 1 luck bout water1.00line city yes 1 luck bout water1.00Cordyceps extract3.003.003.00Echinacea extract2.602.602.60Boswellia extract4.004.004.0