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KR-20260063593-A - GRID FOR FORMING SPATIALLY FRACTIONATED X-RAY AND RADIOTHERAPY APPARATUS HAVING THE SAME

KR20260063593AKR 20260063593 AKR20260063593 AKR 20260063593AKR-20260063593-A

Abstract

A grid for forming a spatially divided X-ray is disclosed. The grid comprises an upper surface located upstream of the X-ray, a lower surface located downstream of the X-ray, and a plurality of elongated holes extending from the upper surface to the lower surface, wherein the holes are arranged radially from the upper surface toward the lower surface.

Inventors

  • 김태헌
  • 김정일
  • 장광호
  • 김근주
  • 김상훈
  • 이정훈
  • 김인수

Assignees

  • 한국전기연구원

Dates

Publication Date
20260507
Application Date
20241030

Claims (11)

  1. As a grid for forming spatially divided X-rays, An upper surface located on the upstream side of the X-ray; A lower surface located on the downstream side of the X-ray; and It includes a plurality of long holes extending from the upper surface to the lower surface, The above holes are a grid arranged radially from the upper surface toward the lower surface.
  2. In claim 1, The above surface includes a convex surface having a first radius of curvature, and The exits of the above holes are grids placed on the above convex surface.
  3. In claim 2, The above upper surface includes a concave surface having a second radius of curvature, and The entrances of the above holes are grids placed on the above concave surface.
  4. In claim 3, The second radius of curvature is a grid smaller than the first radius of curvature.
  5. In claim 4, The first radius of curvature and the second radius of curvature are each a grid representing the distance from the center of the target where X-rays are generated to the convex surface and the concave surface.
  6. In claim 1, The above holes are a grid having the same length as each other.
  7. In claim 1, The above holes are a grid arranged in a continuous direction from the center of the target where X-rays are generated to the center of the entrance of each hole.
  8. In claim 7, A grid in which the entrance width of the above holes is equal to or smaller than the exit width of the above holes.
  9. In claim 8, A grid in which the inlet width of the holes is smaller than the outlet width of the holes, and the difference between the inlet width and the outlet width is within ±10% of the product (t·ra) of the inlet angle (ra) of the holes and the length (t) of the holes.
  10. In claim 1, A grid in which the difference in X-ray radiation doses irradiated through the above holes is less than 10% of the maximum radiation dose.
  11. X-ray target that generates X-rays by an electron beam; A collimator that limits the irradiation area of X-rays generated from the above X-ray target; It includes a grid positioned downstream of the above-mentioned collimator, The above grid is a radiation therapy device that is a grid described in any one of claims 1 to 10.

Description

Grid for forming spatially fractionated X-rays and radiotherapy apparatus having the same The present invention relates to a grid and a radiation therapy device having the same, and more specifically, to a grid for forming spatially divided X-rays and a radiation therapy device having the same. Medical linear accelerator-based radiation therapy devices are medical devices that treat cancer by irradiating tumors located inside a patient's body with high-energy X-rays generated from a linear accelerator. Generally, high-output electromagnetic energy is used to accelerate an electron beam in a linear accelerator, and the accelerated electron beam collides with an X-ray target such as tungsten, generating X-rays through the bremsstrahlung effect. Generally, radiation therapy is performed by irradiating a patient with X-rays generated from a linear accelerator mounted on a rotating gantry, and the X-ray dose is increased to reduce treatment time and enhance treatment efficacy. However, irradiating a patient with high-dose X-rays during radiation therapy can cause radiation toxicity to normal tissues surrounding the tumor. Research is being conducted on techniques to generate spatially divided X-rays to enhance therapeutic effects while suppressing radiation toxicity. When spatially divided X-rays are used in radiation therapy, the peak X-ray dose can be increased while maintaining the same average X-ray dose used for cancer treatment, and the same immunological treatment is possible even in tumor regions that are not irradiated with X-rays, thereby maximizing therapeutic effects with the same average dose. Conventionally, research has been conducted to enhance therapeutic efficacy by placing a perforated metal structure, or grid, in the path through which X-rays generated by a linear accelerator are irradiated to the patient. This structure allows X-rays to pass through only the perforated areas, generating spatially segmented X-rays that are then irradiated to the patient. However, conventional grids cause interference with the X-rays passing through them, resulting in dose loss. In particular, a significant dose difference is observed between X-rays passing through the holes in the central region of the grid and those passing through the holes in the peripheral region. Consequently, the efficient delivery of X-rays intended for treating the tumor area is hindered, thereby adversely affecting the effectiveness of tumor treatment. FIG. 1 is a schematic perspective view for illustrating a radiation therapy device according to one embodiment of the present invention. FIG. 2 is a schematic cross-sectional view illustrating a radiation cancer treatment device and a grid for forming spatially divided X-rays according to one embodiment of the present invention. FIG. 3a is a plan view for explaining the upper surface of a grid according to one embodiment of the present invention. FIG. 3b is a plan view for explaining the lower surface of a grid according to one embodiment of the present invention. FIG. 4a is a schematic cross-sectional view illustrating a hole in a grid according to one embodiment of the present invention. FIG. 4b is a schematic cross-sectional view illustrating a hole in a grid according to another embodiment of the present invention. Figure 5 is a simulation diagram showing the typical two-dimensional distribution of radiation dose of X-rays passing through a collimator and a grid. Figure 6a is a simulation graph showing the radiation dose on a one-dimensional line according to the prior art. FIG. 6b is a simulation graph showing the radiation dose on a one-dimensional line according to an embodiment of the present invention. Hereinafter, embodiments of the present invention will be described in detail with reference to the attached drawings. The embodiments described below are provided as examples to ensure that the concept of the present invention is sufficiently conveyed to those skilled in the art to which the present invention pertains. Accordingly, the present invention is not limited to the embodiments described below and may be embodied in other forms. Throughout the specification, the same reference numerals indicate the same components. FIG. 1 is a schematic perspective view for explaining a radiation therapy device (100) according to one embodiment of the present invention. Referring to FIG. 1, the radiation therapy device (100) according to the present embodiment may include a gantry (121), a collimator assembly (123), and a patient placement table (125) on which a patient (129) is placed. The gantry (121) can rotate around the patient's area of interest. An X-ray generator is placed within the rotatable gantry (121). An electron beam accelerator can be placed within the gantry (121), and the electron beam accelerator can be placed in a horizontal or vertical direction within the gantry (121). If the electron beam accelerator is placed horizontally, the electron beam accelerated in the ho