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KR-20260065096-A - Composition for antioxidant, or preventing or improving acne, skin aging with fermented extract of pine nut exocarp

KR20260065096AKR 20260065096 AKR20260065096 AKR 20260065096AKR-20260065096-A

Abstract

The present invention relates to a composition for antioxidant purposes or for preventing or improving acne and skin wrinkles, comprising a fermented pine nut outer shell extract. The composition according to the present invention possesses excellent antibacterial activity against Propionibacterium acnes strains and has excellent antioxidant and skin wrinkle improvement efficacy, so it can be utilized for improving and preventing acne, skin aging and skin wrinkles caused by free radicals.

Inventors

  • 이윤희

Assignees

  • 이윤희

Dates

Publication Date
20260508
Application Date
20241031

Claims (9)

  1. An antioxidant cosmetic composition comprising a fermented pine nut outer seed coat extract obtained by fermenting the pine nut outer seed coat extract with the Lactobacillus plantarum TYS23-01 strain (Deposit No.: KCTC15710BP).
  2. In paragraph 1, The above cosmetic composition is, A cosmetic composition that prevents skin aging caused by free radicals.
  3. A cosmetic composition for preventing or improving skin wrinkles comprising a fermented pine nut outer shell extract obtained by fermenting the pine nut outer shell extract with the Lactobacillus plantarum TYS23-01 strain (Deposit No.: KCTC15710BP).
  4. A cosmetic composition for preventing or improving acne comprising a fermented pine nut outer shell extract obtained by fermenting the pine nut outer shell extract with the Lactobacillus plantarum TYS23-01 strain (Deposit No.: KCTC15710BP).
  5. A topical skin preparation for preventing or treating acne, comprising as an active ingredient a fermented pine nut outer shell extract obtained by fermenting the pine nut outer shell extract with the Lactobacillus plantarum TYS23-01 strain (Deposit No.: KCTC15710BP).
  6. An antioxidant food composition comprising a fermented pine nut outer seed coat extract obtained by fermenting the pine nut outer seed coat extract with the Lactobacillus plantarum TYS23-01 strain (Deposit No.: KCTC15710BP).
  7. A food composition for preventing or improving skin wrinkles comprising a fermented pine nut outer seed coat extract obtained by fermenting the pine nut outer seed coat extract with the Lactobacillus plantarum TYS23-01 strain (Deposit No.: KCTC15710BP).
  8. A food composition for improving acne comprising a fermented pine nut outer shell extract obtained by fermenting a pine nut outer shell extract with the Lactobacillus plantarum TYS23-01 strain (Deposit No.: KCTC15710BP).
  9. A pharmaceutical composition for preventing or treating acne comprising, as an active ingredient, a fermented pine nut outer shell extract obtained by fermenting the pine nut outer shell extract with the Lactobacillus plantarum TYS23-01 strain (Deposit No.: KCTC15710BP).

Description

Composition for antioxidant, or preventing or improving acne, skin aging with fermented extract of pine nut exocarp The present invention relates to a composition for antioxidant purposes or for preventing or improving acne and skin wrinkles, comprising a fermented extract of the outer shell of a pine nut . Specifically, the present invention provides a composition for antioxidant purposes or for preventing or improving acne and skin wrinkles, comprising a fermented extract of the outer shell of a pine nut obtained by fermenting the outer shell of a pine nut using the Lactobacillus plantarum TYS23-01 strain. With the recent increase in interest in skin care, the occurrence of acne can extend beyond a mere skin condition to lead to various mental health issues, including psychological burden, loss of self-confidence, and depression. While acne primarily occurs on the face, such as the forehead, it can also appear on the chest, back, and shoulders. Acne is a chronic inflammatory disease of the sebaceous glands characterized by the formation of comedones, papules, and pustules; historically, it mainly affected adolescent boys and girls. However, due to factors such as air pollution and drug abuse, it is now occurring regardless of age. Although the exact cause of acne has not yet been definitively identified, it is believed to be caused by hormonal activity, excessive sebum secretion, and bacterial infection. Ultimately, acne can be defined as a complex inflammatory skin disease occurring in the sebaceous glands, hair follicles, and surrounding tissues due to the aforementioned causes, characterized by the appearance of comedones. Comedones refer to spiral-shaped, hardened lumps of sebum that primarily appear on the face, forehead, and bridge of the nose. Inside the comedon, the anaerobic Propionibacteriumacnes , known as the causative agent of acne, grows, while aerobic bacteria such as Staphylococcus epidermidis and Pityrosporum ovale grow on the surface of the comedon. Pests such as ovale and Staphylococcus aureus grow, and various components produced by these bacteria settle on the hair follicles and surrounding skin, causing inflammation. Conventionally, oral or topical medications were used to treat acne. The primary methods involved exfoliating pores using salicylic acid or retinoic acid, a vitamin A derivative, and enhancing the bactericidal effect against acne bacteria using antibiotics such as triclosan. However, salicylic acid is classified as a preservative in Korea and cannot be contained in formulations at a concentration of more than 0.5%, and triclosan causes skin irritation upon contact, so their use is inevitably limited. Meanwhile, the body is exposed to ultraviolet rays and harmful external substances, and thus possesses a natural healing ability to counteract them. Among these, oxidative attack and antioxidant defense are closely coordinated within the body, but in reality, the defense system is not perfect compared to the attack. Consequently, biomolecules such as lipids, proteins, and nucleic acids, which are components of the body, suffer continuous oxidative damage from free radicals, which act as oxidizers, and the products of these oxidation reactions gradually accumulate in the body as one ages. Reactive oxygen species (ROS) are toxic substances produced during the metabolic process of utilizing oxygen inhaled into the body; also known as harmful oxygen, they refer to oxygen with strong oxidizing power that attacks biological tissues. ROS are the primary culprit behind skin aging, as it is known that oxygen inhaled during respiration attacks biological tissues and damages cells. Specifically, during the process of repairing damaged cells through oxygen supply, attacks by ROS prevent the cells from being fully restored, causing them to lose function or die. This also affects skin cell regeneration, ultimately leading to skin aging. Overproduction of reactive oxygen species (ROS) has been reported in the context of UVB exposure, and signaling pathways associated with UVB exposure involve proteins such as MAPKs (mitogen-activated protein kinases), ERK (extracellular signal-regulated kinase), p38 kinase, and JNK (c-Jun amino-terminal kinase), which induce increased expression of NF-κB and AP-1 transcription factors. Additionally, the AP-1 protein is associated with the activation of MMP (matrix metalloproteinase) genes, and the NF-κB protein affects the expression of proinflammatory cytokines such as interleukin. The breakdown of collagen and elastin in aging skin is primarily caused by the increased expression of their degrading enzymes, such as MMP proteins. Additionally, pro-inflammatory cytokines interfere with collagen synthesis and promote its breakdown. Type I collagen is the most abundant protein in the extracellular matrix of connective tissue. The extracellular matrix contains other types of proteins, such as Type III, V, and VII collagen, elastin, proteoglycans, and fibronect