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KR-20260067949-A - Cosmetic composition for improving photoaging and thermalaging and its manufacturing method

KR20260067949AKR 20260067949 AKR20260067949 AKR 20260067949AKR-20260067949-A

Abstract

The present invention, a cosmetic composition for improving photoaging and thermal aging and a method for preparing the same, is characterized by including one or more micelles formed by hydrogen bonding between arginine and one or more saturated fatty acids having 8 to 12 carbon atoms, or micelles formed by hydrogen bonding between arginine and one or more triglycerides containing 8 to 12 carbon atoms, thereby increasing the water solubility and skin penetration through the keratin of arginine, which is a zwitterion, and having a complexly enhanced and synergistic effect for reducing inflammation caused by photoaging and thermal aging, alleviating aging symptoms, and improving skin.

Inventors

  • 권구철
  • 김미정
  • 윤상아

Assignees

  • 서린컴퍼니(주)

Dates

Publication Date
20260513
Application Date
20250205
Priority Date
20241105

Claims (18)

  1. A cosmetic composition for improving photoaging and thermal aging, comprising one or more micelles formed by ion pairs formed by hydrogen bonding between arginine and one or more of saturated fatty acids having 8 to 12 carbon atoms, or micelles formed by ion pairs formed by hydrogen bonding between arginine and one or more of triglycerides containing 8 to 12 carbon atoms.
  2. In paragraph 1, A cosmetic composition for improving photoaging and thermal aging, characterized in that the micelles have an average diameter of 1-10 nm.
  3. In paragraph 1, A cosmetic composition for improving photoaging and thermal aging, characterized by the additional inclusion of a sparingly soluble component within the micelle structure to form a nanovesicle.
  4. In paragraph 3, A cosmetic composition for improving photoaging and thermal aging, characterized in that the above nanovesicles have an average diameter of 100-500 nm.
  5. In paragraph 3, A cosmetic composition for improving photoaging and thermal aging, characterized in that the above-mentioned insoluble component includes one or more of betulin or quercetin.
  6. In paragraphs 1 through 5, A cosmetic composition for improving photoaging and thermal aging, characterized in that the above-mentioned saturated fatty acid having 8 to 12 carbon atoms has a carboxyl group only at the 1st carbon and has a linear structure rather than a branched structure.
  7. In paragraph 6, A cosmetic composition for improving photoaging and thermal aging, characterized in that the saturated fatty acid having a linear structure with 8 to 12 carbon atoms is caprylic acid, capric acid, or lauric acid.
  8. In Paragraph 7, A cosmetic composition for improving photoaging and thermal aging, characterized by additionally including a linear diol having 6 to 12 carbon atoms, having hydroxyl groups at the 1st and 2nd carbon atoms, and not having a branched structure.
  9. In paragraph 8, A cosmetic composition for improving photoaging and thermal aging, characterized in that the linear diol is 1,2-hexanediol.
  10. In Paragraph 7, It includes micelles formed by ion pairs formed by hydrogen bonding between the caprylic acid and the arginine. The above-mentioned insoluble component is betulin, and A cosmetic composition for improving photoaging and thermal aging, characterized by comprising 0.1 to 20 parts by weight of arginine, 0.098 to 20 parts by weight of caprylic acid, 0.002 to 0.5 parts by weight of betulin, and 59.5 to 99.8 parts by weight of water.
  11. In Paragraph 7, It includes micelles formed by ion pairs formed by hydrogen bonding between the caprylic acid and the arginine. The above-mentioned insoluble component is quercetin, and A cosmetic composition for improving photoaging and thermal aging, characterized by comprising 0.1 to 20 parts by weight of arginine, 0.098 to 20 parts by weight of caprylic acid, 0.002 to 2 parts by weight of quercetin, and 58 to 99.8 parts by weight of water.
  12. In Paragraph 7, It includes micelles formed by ion pairs formed by hydrogen bonding between the caprylic acid and the arginine. A cosmetic composition for improving photoaging and thermal aging, characterized in that the caprylic acid and the arginine have a molar ratio of 1:3 to 3:1.
  13. In paragraphs 1 through 5, A cosmetic composition for improving photoaging and thermal aging, characterized in that the triglyceride containing one or more of the above-mentioned saturated fatty acids having 8 to 12 carbon atoms is glyceryl tridecanoate, glyceryl trioctanoate, or caprylic/capric triglyceride.
  14. In Paragraph 13, A cosmetic composition for improving photoaging and thermal aging, characterized by additionally including a linear diol having 6 to 12 carbon atoms, having hydroxyl groups at the 1st and 2nd carbon atoms, and not having a branched structure.
  15. In Paragraph 14, A cosmetic composition for improving photoaging and thermal aging, characterized in that the linear diol is 1,2-hexanediol.
  16. A step in which 0.1 to 20 parts by weight of arginine are added to 59.5 to 99.8 parts by weight of water, and stirred using a homodisper at 1,500 rpm to 2,500 rpm for 15 to 25 minutes to produce a first solution in which arginine is dissolved in water; and A step in which 0.098 to 20 parts by weight of caprylic acid are added to the first solution, heated to 50°C to 90°C, and stirred at 2,000 rpm to 4,000 rpm for 10 to 30 minutes using a homodisper to form micelles by ion pairs formed by hydrogen bonding between the caprylic acid and the arginine; A method for preparing a cosmetic composition for improving photoaging and thermal aging, comprising
  17. A step in which 0.1 to 20 parts by weight of arginine are added to 59.5 to 99.8 parts by weight of water, and stirred using a homodisper at 1,500 rpm to 2,500 rpm for 15 to 25 minutes to produce a first solution in which arginine is dissolved in water; A step in which 0.002 - 0.5 parts by weight of betulin and 0.098 - 20 parts by weight of caprylic acid are heated to 50℃ - 90℃ and stirred using a homodisper at 1,500 rpm - 2,500 rpm for 15 - 25 minutes to produce a solution 2a in which betulin is dissolved in caprylic acid; A step in which the 2a solution is added to the 1st solution and heated to 50°C - 90°C, and stirred at 2,000 rpm - 4,000 rpm for 10 - 30 minutes using a homodisper, thereby forming micelles by ion pairs formed by hydrogen bonding between the caprylic acid and the arginine; and A step in which the betulin is included inside the micelle structure to form a nanovesicle; A method for preparing a cosmetic composition for improving photoaging and thermal aging, comprising
  18. A step in which 0.1 to 20 parts by weight of arginine are added to 58 to 99.8 parts by weight of water, and stirred using a homodisper at 1,500 rpm to 2,500 rpm for 15 to 25 minutes to produce a first solution in which arginine is dissolved in water; A step in which 0.002 to 2 parts by weight of quercetin and 0.098 to 20 parts by weight of caprylic acid are heated to 50℃ to 90℃ and stirred using a homodisper at 1,500 rpm to 2,500 rpm for 15 to 25 minutes to produce a solution 2b in which quercetin is dissolved in caprylic acid; A step in which the 2b solution is added to the 1st solution, heated to 50°C - 90°C, and stirred at 2,000 rpm - 4,000 rpm for 10 - 30 minutes using a homodisper to form micelles by ion pairs formed by hydrogen bonding between the caprylic acid and the arginine; and A step in which the quercetin is included inside the micelle structure to form a nanovesicle; A method for preparing a cosmetic composition for improving photoaging and thermal aging, comprising

Description

Cosmetic composition for improving photoaging and thermalaging and its manufacturing method The present invention relates to a cosmetic composition for improving photoaging and thermal aging, intended to improve skin inflammation or photoaging caused by light sources such as ultraviolet rays, and skin inflammation or thermal aging caused by heat sources such as infrared rays, and a method for manufacturing the same. More specifically, the invention relates to a micelle formed by ion pairs formed by hydrogen bonding between arginine and one or more saturated fatty acids having 8 to 12 carbon atoms, or a micelle formed by ion pairs formed by hydrogen bonding between arginine and one or more triglycerides containing 8 to 12 carbon atoms having saturated fatty acids, wherein the composition possesses zwitterion characteristics and includes a guanidyl group to increase the penetration of arginine, which is difficult to penetrate through the stratum, through the stratum, thereby having improved effects on photoaging and thermal aging, and having complex effects on promoting skin regeneration and alleviating inflammation. The present invention relates to a cosmetic composition for improving photoaging and thermal aging having synergistic effects and a method for manufacturing the same. The skin is the largest tissue in the body and serves as the primary organ for protecting and contacting the body against the external environment and stimuli. It not only acts as the first line of defense against external substances and stimuli but also plays a crucial role in internal metabolism by regulating body temperature and fluid balance. Furthermore, as the first organ visible to the outside, the skin is a vital organ for expressing external beauty. In modern society, this emphasis on external beauty is increasingly becoming as significant as the emphasis on health. This is because, with the rising elderly population, physical beauty has established itself as a standard of judgment symbolizing youth and health; moreover, for the younger generation, this external beauty manifests as confidence and has become a competitive edge that influences their professional performance. For these reasons, active efforts are being made in both academic and industrial fields to prevent skin damage and aging. While the sun is an essential element for the survival of living organisms, excessive exposure to ultraviolet (UV) radiation, due to its high energy, can cause short-term dilation of epidermal capillaries, leading to erythema, heat sensation, pain, swelling, blistering, and epidermal peeling. It also stimulates melanin production, causing tanning. Furthermore, increased skin sensitivity can induce rashes and itching. Chronic exposure causes significant degenerative changes in skin cells, fibrous tissue, and blood vessels, leading to premature skin aging and skin cancer. Specific signs of aging include decreased skin elasticity, wrinkles, and dry, rough skin resulting from a weakened skin barrier. Increased melanin production also causes freckles, moles, dark spots, and brown pigmentation. Recent studies indicate that even short-term exposure to UV radiation can induce inflammation in skin cells. Furthermore, it has recently been reported that thermal energy from infrared rays, which had not previously been identified as a risk, can also cause aging at a level similar to that of ultraviolet rays. In addition, as it has been revealed that thermal aging occurs in high-temperature and dry environments caused by heating, as well as in environments exposed to temperatures above 43 degrees Celsius during showering, awareness of this issue is rising. Recently, due to rapid climate change and environmental pollution, there has been increased exposure to ultraviolet (UV) and infrared (IR) rays. This increased exposure leads to photoaging and thermal aging, prompting the release of various functional cosmetics designed to prevent inflammation caused by these factors or to alleviate symptoms of aging. However, conventional functional cosmetics currently face limitations in effectively mitigating inflammatory factors that increase specifically in response to UV or IR rays, or in their application due to the low stability or poor solubility of specific ingredients designed to eliminate inflammation-causing Reactive Oxygen Species (ROS). Furthermore, conventional ingredients designed to eliminate ROS are not efficiently absorbed into the skin, limiting their ability to suppress inflammation caused by UV and IR rays. Additionally, there have been issues where skin pigmentation caused by melanin, weakened skin elasticity, and dryness resulting from a weakened skin barrier were not effectively resolved. In other words, conventionally known functional cosmetic compositions for improving photoaging and thermal aging have problems such as limitations in usage amounts due to the stability and physical properties of the applied ingredients, or the inability