RU-2861430-C1 - METHOD FOR INCREASING EFFICIENCY OF CARP REARING

Abstract

FIELD: agriculture; fish farming. SUBSTANCE: invention can be used for feeding fish. A thin layer of feed is sprayed with umbelliferone dissolved in distilled water at a dosage of 1 mg/kg of feed. EFFECT: increasing the efficiency of carp rearing, having a positive effect on fish productivity and development. 1 cl, 2 tbl

Inventors

• ARINZHANOV AZAMAT ERSAINOVICH
• MIROSHNIKOVA ELENA PETROVNA
• Kiliakova Iuliia Vladimirovna
• Malenkina Kseniia Aleksandrovna
• Saraikin Aleksandr Ivanovich

Dates

Publication Date

20260505

Application Date

20251208

Claims (1)

1. A method for increasing the efficiency of carp cultivation, characterized by the fact that umbelliferone is used as a feed additive at a dosage of 1 mg/kg of feed, which is pre-dissolved in distilled water and then sprayed on a thin layer of feed.

Description

The invention relates to agriculture, namely to fish farming, and can be used for feeding fish. Umbelliferone (7-hydroxycoumarin) is a widespread coumarin compound found in the flowers, fruits, and roots of almost all higher plants. Umbelliferone is known for its antioxidant (Thabit R.M., El-Aziz, F.EZ.A.A., El-Fadl, A.A. et al. Synthesis and evaluation of nanosized aluminum MOF encapsulating Umbelliferon: assessing antioxidant, anti-inflammatory, and wound healing potential in an earthworm model. BMC Biotechnol. 2024;24:61 doi: 10.1186/s12896-024-00889-8), anti-inflammatory (Wang D., Wang X., Tong W., Cui Y., Li X., Sun H. Umbelliferone Alleviates Lipopolysaccharide-Induced Inflammatory Responses in Acute Lung Injury by Down-Regulating TLR4/MyD88/NF-κB Signaling. Inflammation. 2019;42(2):440-448. doi: 10.1007/s10753-018-00953-4.), antimicrobial (Swetha TK, Pooranachithra M., Subramenium GA, Divya V., Balamurugan K., Pandian SK. Umbelliferone Impedes Biofilm Formation and Virulence of Methicillin-Resistant Staphylococcus epidermidis via Impairment of Initial Attachment and Intercellular Adhesion. Front. Cell. Infect. Microbiol. 2019;9:357. doi: 10.3389/fcimb.2019.00357) and immunomodulatory properties (Changes in immunological and productive parameters in broiler chickens under the influence of biologically active substances from oak bark extract / V.I. Fisinin, A.S. Ushakov, G.K. Duskaev [et al.] // Agricultural Biology. - 2018. - Vol. 53, No. 2. - Pp. 385-392. doi: 10.15389/agrobiology.2018.2.385rus.), and attracts great attention as a potential feed additive (Mixtures of phytochemicals change the productivity and general condition of the body of broiler chickens / G.K. Duskaev, T.A. Klimova, Sh.G. Rakhmatullin [et al.] // Russian Agricultural Science. - 2025. - No. 1. - Pp. 58-62. - doi: 10.31857/S2500262725010106.). A feed additive is known (RU 2719621, A61K 31/047, A61K 31/05, A61K 31/11, 2020) comprising a composition of chemical substances in the following dosages: 4-(3-hydroxy-1-propenyl)-2-methoxyphenol - 2.1 mg; 3,4,5-trimethylhydroxyphenol - 0.84 mg; 4-propyl-1,3-benzenediol - 0.65 mg; 4-hydroxy-3-methoxybenzaldehyde - 0.25 mg; 7-hydroxy-6-methoxy-2H-1-benzopyran-2-one - 0.22 mg; 2H-1-benzopyranone-2 - 0.14 mg per kg of dry matter of the diet. A feed additive is known (RU 2778755, A23K 50/75, 2022), which includes a mixture of chemically pure gamma-octalactone with coumarin, the antibiotic "Biovit" and an electrochemically activated (ECA) aqueous solution of catholyte with a redox potential of Eh = -600 mV and a hydrogen index of pH 9. A feed additive (RU 2804542, A23K 50/10, 2023) is known, consisting of phytochemicals: trans-cinnamic aldehyde, vanillin, 7-hydroxycoumarin, quercetin dihydrate. A method for increasing productivity is known (RU 2806914, A23K 50/75, A23K 10/30, 2023), according to which a feed additive containing 7-hydroxycoumarin at a dosage of 3 mg/kg of feed per day is fed as part of the diet. A method for increasing productivity is known (RU 2807760, A23K 50/75, 2023), according to which a feed additive is fed, including a composition of 7-hydroxycoumarin compounds (0.3 mg/kg live weight) and vanillin (0.3 mg/kg live weight). A feeding method is known (RU 2790872, A23K 10/30, A23K 50/75, 2023), the essence of which lies in feeding as part of the diet a feed additive including a composition of quercetin at a dosage of 2.5 mg/kg of live weight per day and 7-hydroxycoumarin at a dosage of 0.1 mg/kg of live weight per day. A method for increasing productivity is known (RU 2838262, IPC A23K 50/75, 2025), according to which a feed additive is fed, including a combination of phytochemicals from chemically pure gamma-octalactone (at a dosage of 0.1 ml/kg of feed) and cinnamaldehyde (at a dosage of 55 mg/kg of feed). The disadvantage of these methods is their limited scope of application, as they are used only for broiler chickens and cattle. The closest to the proposed one in terms of technical essence is the use of vanillin as a feed additive for fish (RU 2833918, A23K 50/80, 2025) at a dosage of 250 mg/kg of feed. The technical result is an increase in the efficiency of carp cultivation. The task is solved by feeding feed, a thin layer of which is sprayed with umbelliferone (CAS RN 93-35-6, Tokyo Chemical Industry Co., LTD, Japan) dissolved in distilled water at a dosage of 1 mg/kg of feed. To implement the method, studies were conducted at the Department of Biotechnology of Animal Raw Materials and Aquaculture of the Orenburg State University, within which 4 groups of carp were formed (n=10): the control group received the basic diet (BD), the 1st experimental group - BD + Umbelliferone at a dosage of 1.0 mg/kg of feed, the 2nd experimental group - BD + Umbelliferone at a dosage of 2.0 mg/kg of feed, the 3rd experimental group - BD + Umbelliferone at a dosage of 3.0 mg/kg of feed. The compound feed for carp fish KRK-110-1 (OJSC Orenburg Feed Mill, Orenburg) was used as the feed addi