RU-2861502-C1 - METHOD FOR TREATING TROPHIC ULCERS IN DIABETIC FOOT

Abstract

FIELD: medicine. SUBSTANCE: invention relates to therapeutic methods of treatment, and can be used for treating trophic ulcers in diabetic foot. While the patient is taking oral antibiotics for a course of 10 days per month, the surface of the trophic ulcer is treated twice a day with hydrogen peroxide, then with a jet of an aqueous solution of chlorhexidine bigluconate, followed by the application of a paste-like mixture consisting of zinc oxide powder and Betadine 10% solution, taken in a ratio of 1:3. Starting from day 10 after the first treatment of the ulcer surface with hydrogen peroxide and an aqueous solution of chlorhexidine bigluconate on that day, Argosulfan cream is applied to the edges of the ulcer, and the paste-like mixture of zinc oxide powder and Betadine 10% is continued to be applied to the ulcer. From day 16 of treatment, the periulcer skin area is exposed to visible red light radiation with a wavelength of 630-660 nm once a week for 10 minutes. From day 31 to day 90, a dressing moistened with furacilin solution is applied once a week, leaving it on the wound until dry. EFFECT: conservative treatment of trophic ulcers in diabetic foot, simplicity of implementation, and availability of materials. 1 cl, 9 dwg, 1 ex

Inventors

• Mudrova Olga Aleksandrovna

Dates

Publication Date

20260505

Application Date

20251028

Claims (1)

1. A method for treating trophic ulcers in diabetic foot, comprising treating the surface of the trophic ulcer, exposing the skin of the periulcer area to visible red light radiation and administering drug therapy, characterized in that, while the patient is taking antibiotics orally for 10 days a month, the surface of the trophic ulcer is treated with hydrogen peroxide twice a day, then with an aqueous solution of chlorhexidine bigluconate in a jet, followed by applying a paste-like mixture consisting of zinc oxide powder and a 10% Betadine solution taken in a 1:3 ratio; starting from the 10th day after the first treatment of the ulcer surface that day with hydrogen peroxide and an aqueous solution of chlorhexidine bigluconate, Argosulfan cream is applied to the edges of the ulcer, and the paste-like mixture of zinc oxide powder and 10% Betadine is continued to be applied to the ulcer; From the 16th day of treatment, the skin of the periulcer area is exposed to visible red light with a wavelength of 630-660 nm once a week for 10 minutes; from the 31st to the 90th day, a bandage soaked in a furacilin solution is applied once a week, leaving it on the wound until it dries.

Description

The invention relates to medicine, namely to therapeutic methods of treatment, and can be used for the local treatment of trophic ulcers in diabetic foot. By 2025, the number of people with diabetes in Russia will have increased from 2.59 million to 4.51 million. Diabetic foot syndrome, caused by this condition, affects approximately 8-10% of patients with diabetes (according to forecasts ©Bulletin of Medical Internet Conferences, 2013 www.medconfer.com). The diabetic foot is characterized by inflammatory and necrotic changes in the soft tissues and bones of the foot, caused by disruption of the blood supply and innervation due to ischemia and neuropathy, as well as infection. All of this can lead to lower limb amputation. The threat of limb amputation makes the treatment of trophic ulcers in diabetic feet a pressing issue. A “Method for treating purulent-inflammatory diseases in diabetes mellitus” is known (patent RU 2229301), which includes traditional antibacterial therapy in combination with hypoglycemic drugs, using the drug Baktisporin, which contains from 1 x 109 to 5 x 109 cells/ml of the Bacillus subtilis 3H strain in 1 dose orally according to the following regimen: 2-3 doses 2-3 times a day for 10-20 days. A method is known (patent RU 2174389), which consists of local application to the surface of trophic wounds and long-term non-healing purulent wounds of a composition in the following ratio by weight %: collagenase 160-200 E; gentamicin sulfate 0.08-0.1; polyethylene oxide-400 66.0-68.0; polyethylene oxide-1500 16.5-17.0; glycerin 10.0-10.1. A method for treating trophic ulcers and long-term non-healing purulent wounds is known (patent RU 2545724), which involves treating the wound with an antiseptic, namely 3.0-1.5% hydrogen peroxide, then, without drying the wound, applying a bandage with the agent "Ichthyosin", obtained from streptocide powder 0.5-2.5 g and ichthyol ointment 5.0-10.0 g, dissolved in 94.5-87.5 ml of castor oil, the agent is applied 1 time per day, the course of treatment is 16 days. A method for treating trophic ulcers and long-term non-healing wounds is known (patent RU 2231377), including exposure to low-intensity laser radiation in combination with a constant magnetic field, while against the background of drug therapy after sanitizing the ulcer or wound with a 0.02% solution of chlorhexidine, a sterile gauze napkin is applied to the surface of the defect, on which two emitters with magnetic attachments are placed, and irradiation is carried out for 5 minutes with infrared pulsed laser radiation in the frequency range from 2 Hz to 12 kHz with a wavelength of 0.89 μm, after which, for 5 minutes from a distance of no more than 5 mm, remote irradiation is simultaneously performed with continuous laser radiation in the visible range of the spectrum and infrared pulsed radiation in the frequency range from 18 to 30 kHz, and in the phase of necrosis and inflammation, the ulcer or wound surface is exposed to laser radiation in the visible range spectrum with a wavelength of 0.44 to 0.52 μm and then apply the drainage sorbent "lysosorb" or "gelevin", in the cleansing and regeneration phase, laser radiation is applied in the visible range of the spectrum with a wavelength of 0.57 to 0.63 μm, then a wound dressing "digispon" is applied, in the epithelialization and scarring phase, laser radiation is applied in the visible range of the spectrum with a wavelength of 0.63 to 0.64 μm, then a wound dressing "geschispon" is applied, after which the defect is covered with a sterile gauze napkin. The closest to the declared method in terms of technical essence and the achieved result, chosen as a prototype, is the method treatment of trophic ulcers (patent RU 2179043), including the treatment of the surface of the trophic ulcer and subsequent drug therapy, ozone therapy, while additionally conducting contact exposure to the skin of the periulcer area with radiation in the region of visible red light with a wavelength of 640 nm and invisible IR radiation with a wavelength of 840-950 nm, slowly moving the sensor of the LED device along the perimeter of the ulcer defect for 10 minutes, then affecting the ulcer defect with an ozone-air mixture with an ozone concentration of 50 mg / l for 15-20 minutes, after which the surface of the ulcer defect is covered with a polyacrylamide gel plate saturated with solutions of antiseptics and antibiotics, fix the plate and during the day, irradiation is carried out twice more using the supravascular technique on the vessels of the popliteal region, for 10 minutes each. The objective of the invention is to expand the range of methods for treating trophic ulcers in diabetic foot. The technical result is the creation of a method for the conservative treatment of trophic ulcers in diabetic feet, which is simple to implement and is carried out using available materials. The specified technical result is achieved by a method for treating trophic ulcers in diabet