RU-2861517-C1 - METHOD FOR PREVENTING SECONDARY AND RECURRENT CARIES IN TREATMENT OF CARIOUS LESIONS

RU2861517C1RU 2861517 C1RU2861517 C1RU 2861517C1RU-2861517-C1

Abstract

FIELD: medicine; therapeutic dentistry. SUBSTANCE: invention is intended for use in minimally invasive treatment of carious lesions and prevention of secondary and recurrent caries. Instrumental and medicamentous treatment of the carious cavity and permanent filling with a glass ionomer cement are performed. The glass ionomer cement used is 'Tsemion', which is pre-wetted in a crucible with a magnetite (Fe 3 O 4 ) hydrosol solution with a mass concentration of 4 ppm, containing dispersed phase nanoparticles of size 1-3 nm, in a ratio of 0.33 g of solution per 1 g of cement. The crucible with the wetted cement is then dried in a drying oven at a temperature of 388±2 K for 30 minutes. After cooling, the mixture is additionally diluted with 'Tsemion' brand liquid in a mass ratio of 3:1 until a homogeneous paste is formed, followed by permanent filling of the carious cavity. EFFECT: possibility of preventing the development of secondary and recurrent caries, maintaining the integrity of the tooth for a long period of time, and improving the patient's quality of life. 1 cl, 1 ex

Inventors

Rumiantsev Vitalii Anatolevich
Andreev Aleksei Alekseevich
Frolov Georgii Aleksandrovich
Abdukodirov Abdulla Abdumalik Ugli

Dates

Publication Date: 20260505
Application Date: 20251017

Claims (1)

A method for preventing secondary and recurrent caries in the treatment of carious lesions, including instrumental and medicinal treatment of the carious cavity, permanent filling with glass ionomer cement, characterized in that Cemion is used as the glass ionomer cement, wherein the Cemion cement is preliminarily moistened in a crucible with a solution of magnetite hydrosol (Fe 3 O 4 ) with a mass concentration of 4 ppm, containing dispersed phase nanoparticles of 1-3 nm in size, in a ratio of 0.33 g of solution per 1 g of cement, then the crucible with the moistened cement is dried in a drying cabinet at a temperature of 388 ± 2 K for 30 minutes, after cooling the mixture is additionally diluted with Cemion brand liquid in a mass ratio of 3: 1 until a homogeneous paste is formed, followed by permanent filling of the carious cavity.

Description

The invention relates to medicine, namely to therapeutic dentistry, and is intended for minimally invasive treatment of carious lesions and prevention of secondary and recurrent caries. It is known that after mechanical treatment of a carious cavity, cariogenic microorganisms remain in it, which, along with the remains of organic tissue, destroyed hydroxyapatite crystals (dentin sawdust), form the so-called “smear layer”. The antibacterial effect of magnetite (Fe 3 O 4 , H 2 O) is known from the prior art. It is explained by the following factors. Firstly, the magnetic attraction of magnetite nanoparticles to the microbiota leads to the maximum concentration of glass ionomer cement in the bacterial focus, the release of metal ions and the disintegration of bacteria, which promotes the maximum penetration of cement into the microbial mass with the subsequent release of fluorides that inhibit the growth of microorganisms. Secondly, local alkalization of microbial colonies due to an increase in the acidity of the environment (hereinafter referred to as pH), which occurs at the stage of cement thickening, also contributes to the inhibition of the growth of microbiota [Rumyantsev V.A., Andreev A.A., Frolov G.A., Leontyeva A.V. Evaluation of the antibacterial activity of polyalkenate cement modified with metal-containing nanoparticles. Postgraduate Bulletin of the Volga Region. 2025; 25(2): 52-55]. Currently, the main method for inhibiting cariogenic microbiota is antiseptic treatment of the carious cavity and the use of temporary therapeutic liners. For antiseptic treatment in clinical practice, antiseptic solutions are most often used: hydrogen peroxide, furacilin, chlorhexidine, which are used to rinse the cavity formed using burs [Kirsh K.D., Adamchik A.A., Ivaschenko V.A. et al. Laboratory study of the antimicrobial efficacy of antiseptics in the treatment of caries. Institute of Dentistry. 2024. No. 2 (103). pp. 88-89.]. However, the disadvantages of this method include the low effectiveness of antimicrobial treatment of the walls and floor of the tooth cavity and the lack of prolonged-action antiseptics. The antiseptic preparations and procedures used act briefly and superficially only on the "smear layer" of dentin [Schwendicke F., et al. Marginal integrity and secondary caries of selectively excavated teeth in vitro // Journal of Dentistry. 2014. No. 42-10 – P. 1261-1268]. The closest approach, chosen as a prototype, is a method for preventing dental caries recurrence. This method involves instrumental and medicinal treatment of the tooth cavity, temporary exposure to an antimicrobial agent, followed by permanent filling. A mixture of calcium hydroxycuprate and a hydrosol of silver nanoparticles measuring 1-10 nm is applied to the cavity floor and walls for 24 hours and sealed with a temporary insulating filling material. After 24 hours, during the second visit, the temporary filling and the medicinal agent are removed from the cavity, and a permanent filling is performed (RU 2839223, published April 28, 2025). The disadvantage of the prototype is the need for a repeat visit to the dentist for permanent filling. The objective of this technical solution is to completely inhibit cariogenic microbiota from the bottom and walls of the formed carious cavity during the permanent filling stage in order to prevent secondary and recurrent caries, maintain the integrity of the tooth over a long period of time, and improve the patient's quality of life. This problem is solved due to the fact that in the method of preventing secondary and recurrent caries in the treatment of carious lesions, including instrumental and medicinal treatment of the carious cavity, permanent filling with glass ionomer cement, differences are provided in that "Cemion" is used as glass ionomer cement, while the "Cemion" cement is preliminarily moistened in a crucible with a solution of magnetite hydrosol (Fe 3 O 4 ) with a mass concentration of 4 ppm, containing dispersed phase nanoparticles of 1-3 nm in size, in a ratio of 0.33 g of solution per 1 g of cement, then the crucible with the moistened cement is dried in a drying oven at a temperature of 388 ± 2 K for 30 minutes, after cooling the mixture is additionally diluted with Cemion brand liquid in a mass ratio of 3: 1 until a homogeneous paste is formed, followed by constant filling the carious cavity. The technical result consists in improving the quality of inhibition of persistent cariogenic microbiota from the bottom and walls of the formed carious cavity, reducing the duration of treatment due to performing filling in one stage instead of two. The essence of the invention is that after instrumental and medicinal treatment of a carious tooth cavity, glass ionomer cement "Cemion" is placed on the bottom and walls of the cavity. The cement is moistened with a magnetite hydrosol solution ( Fe3O4 ) with a mass concentration of 4 ppm, containing dispersed phase nanoparticles of 1-3 nm i