RU-2861659-C1 - METHOD FOR FEEDING BROILER CHICKENS

RU2861659C1RU 2861659 C1RU2861659 C1RU 2861659C1RU-2861659-C1

Abstract

FIELD: agriculture. SUBSTANCE: invention relates to raising broiler chickens for meat. A feed additive for poultry is characterised in that from the age of 7 days for the entire growing period, broiler chickens are fed a feed additive as part of their diet. The feed additive includes a combination of 7-hydroxycoumarin at a dosage of 2 mg/kg of feed and a zinc-glycine complex at a dosage of 100 mg/kg of feed per day. EFFECT: increasing the productivity of broilers, as well as reducing feed costs per 1 kg of live weight gain. 1 cl, 5 tbl, 1 ex

Inventors

RAKHMATULLIN SHAMIL GAFIULLOVICH
Deriabin Dmitrii Gennadevich
NURZHANOV BAER SEREKPAEVICH
Klimova Tatiana Andreevna
Kurilkina Marina Iakovlevna
Atlanderova Kseniia Nikolaevna
DUSKAEV GALIMZHAN KALIKHANOVICH

Dates

Publication Date: 20260507
Application Date: 20251021

Claims (1)

A method of feeding broiler chickens, characterized by the fact that broiler chickens are fed, together with the main diet, once a day throughout the entire growing period, starting from the age of 7 days, a combination of 7-hydroxycoumarin at a dosage of 2 mg/kg of feed and a zinc-glycine complex at a dosage of 100 mg/kg of feed.

Description

The invention relates to agriculture, specifically to the raising of broiler chickens for meat. The method involves feeding the chickens a diet containing 7-hydroxycoumarin at a dosage of 2.0 mg/kg of feed and a zinc glycine complex at a dosage of 100 mg/kg of feed. Modern feeding of farm animals and poultry, amid the ban on the use of feed antibiotics, has prompted the search for alternatives, including medicinal plants. However, their use in the form of extracts or dry mixtures in diets is controversial, as the chemical composition of plants is variable [1-3]. Therefore, the use of individual phytochemicals is more promising. Coumarin, its ring system (benzopyran-2-one or chromen-2-one), present in many natural products (medicinal plants), has a variety of pharmacological properties [4, 5]. A method of using coumarin to inhibit various lux/luxr type quorum sensing systems in bacteria is known [6]. The use of 7,8-dihydroxy-4-methylcoumarin as an inhibitor of the LuxI/LuxR type quorum sensing system in bacteria is considered. Another study noted that 7-hydroxycoumarin exhibits antibacterial activity: MIC 50 = 0.497 mg/ml and MIC 100 = 1.267 mg/ml. At the same time, subinhibitory concentrations of this compound provided an anti-QS effect [7]. A "Method for Increasing the Productivity of Agricultural Poultry" is known: broiler chickens are fed 7-hydroxycoumarin at a dose of 3 mg/kg of feed daily, along with their basic diet, throughout the entire growing period, starting at 7 days of age. This invention will increase broiler productivity and reduce feed costs per kg of live weight gain [8]. The umbelliferone used in the experiment, known as 7-hydroxycoumarin [9], is a naturally occurring coumarin found in plants, primarily in the Apiaceae family, and possesses a wide range of pharmacological properties. Its derivatives have great potential for therapeutic use due to their broad spectrum of biological activity, including anti-inflammatory, antioxidant, neuroprotective, antipsychotic, antiepileptic, antidiabetic, antimicrobial, antiviral, and antiproliferative effects. Previously [10], the inclusion of coumarin and a coumarin-probiotic mixture in the diet improved growth performance and reduced feed consumption per kg of live weight gain. A decrease in leukocyte count, an increase in creatinine and triglyceride (CO) levels, and changes in aminotransferase and transpeptidase activity were observed. The coumarin nucleus is a recurring element in both natural and synthetic compounds that exhibit a wide range of biological properties, including anticoagulant, anti-inflammatory, antioxidant, antiviral, antimicrobial, and anticancer properties, as well as enzyme inhibitors. On the other hand, it has been reported [11] that the incorporation of metal ions into coumarin derivatives can enhance the activity of such complexes compared to coumarin-based ligands. Combinations of biologically active substances from medicinal plants and microelements when fed improve protein, carbohydrate, lipid, and mineral metabolism in animals [12]. The use of organic zinc is of interest in this regard. Organic zinc enhances its absorption in the small intestine of broilers [13], significantly improves the growth performance of monogastric animals [14], broiler chickens, some carcass parameters, health and meat quality [15], increases the concentration of zinc in eggs [16], egg production, improves the viability of rooster sperm and egg fertilization [17]. In other studies, organic zinc [18] increased growth performance (at a dose of 80 mg/kg), improved intestinal histomorphology, and reduced Zn excretion into the environment. A protective effect of grape seed powder (Vitis vinifera) and a zinc-glycine complex on growth performance and intestinal health of broilers after infection with Eimeria tenella was noted [19]. The essence of the proposed invention consists in feeding broiler chickens, as part of a diet, 7-hydroxycoumarin at a dosage of 2 mg/kg of feed and a zinc glycine complex at a dosage of 100 mg/kg of feed per day, which contributes to an increase in the productivity of the bird. Thus, in comparison with the above-mentioned technical solutions [6-8], the claimed invention has a number of significant differences that meet the requirement of novelty. 1. The invention relates to agriculture; 2. The studies were carried out on broiler chickens; 3. The proposed invention uses 7-hydroxycoumarin at a dosage of 2 mg/kg of feed per day as part of a complete feed for broiler chickens, together with a zinc glycine complex at a dosage of 100 mg/kg of feed; 4. The combined use of 7-hydroxycoumarin with zinc glycine complex helps to increase the productivity of broiler chickens. Example The studies were conducted at the shared scientific equipment center of the Federal Scientific Center for Biotechnology, Russian Academy of Sciences. The subjects of the study were 7-day-old broiler chickens of the ROSS 308 cross, n = 120 (three replicates, 3