US-12616641-B2 - Medicament container having a flexible sidewall

Abstract

A medicament container including at least one sidewall and an extension is provided. The extension may be rigid in comparison to sidewalls that form the volume of the container. The extension may extend substantially into the volume of the container to a central region of the container. The container may include one or more ribs formed in the sidewalls to provide structural rigidity to the sidewalls.

Inventors

• Yuki Hayashi
• Masaya Nakamura

Assignees

• ELI LILLY AND COMPANY
• FUJIMORI KOGYO CO., LTD.

Dates

Publication Date

20260505

Application Date

20220427

Claims (20)

1. 1 . A medicament container comprising: a sidewall at least partially defining an interior volume of the medicament container; a spout for outflow of medicament from the interior volume of the medicament container, the spout being coupled to the sidewall; and an extension coupled to the spout and having a pair of opposing faces, the extension being disposed inside the interior volume of the medicament container and including a passage in fluid communication with the interior volume of the medicament container and the spout, the sidewall having a greater flexibility than the extension such that the medicament container has a collapsed state when empty and an expanded state when full, wherein the sidewall is configured to move as medicament flows out of the interior volume of the medicament container through the spout, wherein the extension has a first end adjacent the spout and a second end opposite the first end, the opposing faces of the extension tapering to an edge at the second end, and wherein a height of the extension measured from the first end to the second end along a central axis of the spout is at least one-fourth of a sidewall height, the sidewall height being measured along a dimension parallel to the central axis of the spout when the medicament container is in the expanded state.
2. 2 . The medicament container of claim 1 , wherein the extension extends centrally along the central axis of the spout.
3. 3 . The medicament container of claim 1 , wherein the height of the extension is at least one half of the sidewall height.
4. 4 . The medicament container of claim 1 , the passage extending through the extension from the second end to the first end and having a notched or indented opening at the second end.
5. 5 . The medicament container of claim 1 , wherein the passage has a fully enclosed interior sidewall.
6. 6 . The medicament container of claim 5 , wherein the interior sidewall includes at least one opening positioned between the first end and the second end of the extension, and the interior sidewall is in fluid communication with the interior volume of the container through the at least one opening.
7. 7 . The medicament container of claim 1 , wherein the extension further comprises a plurality of grooves in fluid communication with the passage.
8. 8 . The medicament container of claim 1 , wherein the sidewall comprises a first rib projecting into the interior volume of the medicament container.
9. 9 . The medicament container of claim 1 , wherein the sidewall comprises a first rib projecting out of the medicament container.
10. 10 . The medicament container of claim 8 , wherein the first rib extends parallel to an outflow direction through the spout.
11. 11 . The medicament container of claim 8 , further comprising a second rib, the second rib extending in a direction at an angle between 0 degrees and 90 degrees relative to an extending direction of the first rib.
12. 12 . The medicament container of claim 8 , where a cross-section of the first rib taken along a longitudinal axis of the first rib is elliptical.
13. 13 . A medicament container comprising: a sidewall at least partially defining an interior volume of the medicament container; a spout for outflow of medicament from the interior volume of the medicament container, the spout being coupled to the sidewall; and an extension coupled to the spout, the extension being disposed inside the interior volume of the medicament container and including a passage in fluid communication with the interior volume of the medicament container and the spout, and the sidewall having a greater flexibility than the extension such that the medicament container has a collapsed state when empty and an expanded state when full, wherein the sidewall is configured to move as medicament flows out of the interior volume of the medicament container through the spout, wherein the extension comprises a first portion having a first end and a second portion having a second end, the first end being closer to the spout than the second end is to the spout, the passage having an opening at the second end, and wherein a cross-sectional area of the extension measured normal to a central axis of the spout is greater at the first portion than at the second portion, the cross-sectional area of the second portion decreasing along the central axis moving away from the spout such that the extension tapers towards the second end, the central axis being parallel to an outflow direction through the spout.
14. 14 . The medicament container of claim 13 , wherein a height of the extension measured along the central axis of the spout is at least one-fourth of a sidewall height, the sidewall height being measured along a dimension parallel to the central axis of the spout when the medicament container is in the expanded state.
15. 15 . The medicament container of claim 13 , wherein the extension extends centrally along the central axis of the spout.
16. 16 . The medicament container of claim 13 , wherein the cross-sectional area of the second portion of the extension continuously decreases such that the extension tapers to an edge at the second end of the extension.
17. 17 . The medicament container of claim 13 , wherein the cross-sectional area of the first portion of the extension is constant from the first end to the second portion of the extension.
18. 18 . The medicament container of claim 13 , wherein a cross-section of the extension normal to the central axis of the spout is hexagonal at the first end.
19. 19 . The medicament container of claim 13 , wherein a cross-section of the extension normal to the central axis of the spout is lens-shaped adjacent to the second end.
20. 20 . The medicament container of claim 13 , wherein the extension further comprises a first edge and a second edge, the first edge disposed on one side of the spout and the second edge disposed on an opposing side of the spout, wherein the first edge and second edge of the first portion of the extension are parallel to the central axis of the spout.

Description

FIELD Disclosed embodiments are related to medicament containers and related methods of use. BACKGROUND Medicament containers are used to hold therapeutic fluid. Such therapeutic fluids may be delivered to a patient via parenteral delivery (e.g. subcutaneous injection, intramuscular injection, intravenous injection), via enteral delivery (e.g. by a gastric feeding tube or a duodenal feeding tube), or by any other suitable route of administration. Medicament containers may be configured to controllably release the therapeutic fluid for delivery into the patient. Health providers typically designate a prescribed amount of medication to be administered to the patient. SUMMARY In some embodiments, a medicament container comprises a sidewall, a spout coupled to the sidewall, and an extension coupled to the spout. The sidewall may at least partially define an interior volume of the medicament container. The spout may be configured for outflow of medicament from the interior volume of the medicament container. The extension may be disposed inside the interior volume of the medicament container. The sidewall may have greater flexibility than the extension such that the medicament container has a collapsed state when empty and an expanded state when full. The sidewall may be configured to move as the medicament flows out of the interior volume of the medicament container through the spout. A height of the extension measured along a central axis of the spout may be at least a fourth of the sidewall height, measured along a dimension parallel to the central axis of the spout when the medicament container is in the expanded state. In some embodiments, a medicament container comprises a sidewall, a spout coupled to the sidewall, and an extension coupled to the spout. The sidewall may at least partially define an interior volume of the medicament container. The spout may be configured for outflow of medicament from the interior volume of the medicament container. The extension may be disposed inside the interior volume of the medicament container. The sidewall may have greater flexibility than the extension such that the medicament container has a collapsed state when empty and an expanded state when full. The sidewall may be configured to move as the medicament flows out of the interior volume of the medicament container through the spout. The extension may comprise a first end and a second end, wherein the first end is closer to the spout than the second end is to the spout. A cross-sectional area of the extension measured normal to a central axis of the spout may be greater at the first end than at the second end, wherein the central axis may be parallel to an outflow direction through the spout. It should be appreciated that the foregoing concepts, and additional concepts discussed below, may be arranged in any suitable combination, as the present disclosure is not limited in this respect. Further, other advantages and novel features of the present disclosure will become apparent from the following detailed description of various non-limiting embodiments when considered in conjunction with the accompanying figures. BRIEF DESCRIPTION OF DRAWINGS The accompanying drawings are not intended to be drawn to scale. In the drawings, each identical or nearly identical component that is illustrated in various figures may be represented by a like numeral. For purposes of clarity, not every component may be labeled in every drawing. In the drawings: FIG. 1 is a perspective top view of one embodiment of a medicament container; FIG. 2 is a front view of the medicament container of FIG. 1; FIG. 3 is a front view of another embodiment of a medicament container; FIG. 4 is a perspective front view of yet another embodiment of a medicament container; FIGS. 5A-5C are a series of perspective cross-sectional views of the medicament container of FIG. 4 taken along A-A, B-B, and C-C respectively; FIG. 6A is a cross-sectional view of the medicament container of FIG. 4 taken along D-D; FIG. 6B is a right side view of the medicament container of FIG. 4; FIG. 7A is a perspective top view of yet another embodiment of a medicament container; FIG. 7B is a front view of the extension of the medicament container of FIG. 7A; FIG. 8A is a front view of yet another embodiment of a medicament container; FIG. 8B is a perspective top view of the spout and extension of the medicament container of FIG. 8A; FIG. 8C is a right side view of the spout and extension of the medicament container of FIG. 8A; FIG. 9A is a perspective top view of yet another embodiment of a medicament container; FIG. 9B is a cross-sectional view of the medicament container of FIG. 9A taken along F-F; FIG. 9C is a cross-sectional view of the medicament container of FIG. 9A taken along G-G; FIG. 10 is a perspective top view of yet another embodiment of a medicament container; FIG. 11 is a front view of yet another embodiment of a medicament container; and FIG. 12 is a front view of yet