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US-12616646-B2 - Use of rochelle salt

US12616646B2US 12616646 B2US12616646 B2US 12616646B2US-12616646-B2

Abstract

The present invention relates to new uses of seignette salt and can be used in the field of dental and oral care products.

Inventors

  • Elena Yur'evna BELOUS
  • Angelina Dmitrievna IVANOVA

Assignees

  • SkyLab AG

Dates

Publication Date
20260505
Application Date
20211215
Priority Date
20211122

Claims (18)

  1. 1 . A toothpaste, comprising: purified water 20-80 wt %; thickener 0.5-1.5 wt %; potassium sodium tartrate (seignette salt) 0.01-5 wt %; abrasive 0.01-20%; preservative 0.01-0.5 wt %; and surfactant 0.01-1 wt %.
  2. 2 . The toothpaste of claim 1 , further comprising glycerol 1-15 wt %.
  3. 3 . The toothpaste of claim 1 , further comprising moisturizer 10-30 wt %.
  4. 4 . The toothpaste of claim 3 , wherein the moisturizer is sorbitol.
  5. 5 . The toothpaste of claim 1 , wherein the thickener is sodium carboxylmethylcellulose.
  6. 6 . The toothpaste of claim 5 , further comprising a second thickener of xanthan gum 0.1-0.5 wt %.
  7. 7 . The toothpaste of claim 1 , further comprising a dry extract of Stevia 0.01-1 wt %.
  8. 8 . The toothpaste of claim 1 , further comprising a sweetener 0.01-1 wt %.
  9. 9 . The toothpaste of claim 1 , further comprising trimethylglycine 0.01-1 wt %.
  10. 10 . The toothpaste of claim 1 , wherein the abrasive is silicon dioxide.
  11. 11 . The toothpaste of claim 1 , wherein the surfactant is lauroylsarcosinate.
  12. 12 . The toothpaste of claim 1 , wherein the preservative is bisabolol.
  13. 13 . The toothpaste of claim 1 , wherein the seignette salt is 0.1-2.5 wt %.
  14. 14 . The toothpaste of claim 1 , wherein the seignette salt is 0.5-1.5 wt %.
  15. 15 . A toothpaste, comprising: water 20-80 wt %; potassium sodium tartrate (seignette salt) 0.01-5 wt %; abrasive 0.01-30 wt %; and surfactant 0.01-1 wt %.
  16. 16 . The toothpaste of claim 15 , further comprising a thickener 0.5-1.5 wt %.
  17. 17 . The toothpaste of claim 15 , further comprising a preservative 0.01-0.5 wt %.
  18. 18 . The toothpaste of claim 15 , wherein the abrasive is 0.01-20 wt %.

Description

FIELD OF THE INVENTION The present invention relates to new uses of seignette salt and can be used in the field of dental care products. PRIOR ART The phenomenon of occurrence of electric polarization in crystals as a result of mechanical strain—or piezoelectric effect—in the recent years has become widely spread in instrumental dentistry both in dental surgical procedures and in teeth whitening [1-5]. The latter direction is based on use of ultrasound scalers [1]. Under the impact of electric current materials possessing piezoelectric properties start to deform. “Inverse piezoelectric effect” is observed. Electric pulses induce microvibrations on piezoelectric materials that can be used for oral care procedures: removal of supragingival deposits—dental tartar and plaque, subgingival deposits. As tooth enamel whitening and tone levelling, removal of pigments from the upper dentine layer remains one of the most popular and in-demand effects of oral hygiene, and professional procedures are expensive services and take a lot of time, the authors offer a new approach to teeth cleaning and whitening as part of daily hygiene also based on piezoelectric effects. With this aim it is offered to use substances possessing piezoelectric properties—piezoelectric materials—as components of formulations of whitening toothpastes and other oral care products [6]. The mechanism of their action during teeth brushing consists in the following. In the process of daily hygienic procedures a manual or electric toothbrush exert mechanical impact on enamel. Piezoelectric materials contained in toothpaste are ultra-sensitive to mechanical vibrations. Electric polarization takes place in such crystals in case of tension and compression in certain directions. As a result, electric charges of both signs appear on their surfaces. In some piezoelectric crystals the lattice of positive ions in the state of thermodynamic equilibrium is displaced with respect to the lattice of negative ions in such a way that the crystals are electrically polarized even in absence of an electric field. The effect of spontaneous polarization is concealed with free surface charges present in the medium. The polarization amplitude in this state will be reduced owing to negative voltage. Deformation of crystals of piezoelectric materials during teeth brushing can lead to redistribution of electric charges and release of extra-charges from the surface. As a result of getting into an aqueous medium excessive charges can lead to generation of reactive oxygen species—·OH and ·O2− [7]. Under maximum mechanical strain there is reduction of the number of bound (polarization) charges. Release of charges will be observed till achievement of a new equilibrium state by the piezoelectric material [8]. With reduction of the impact (change of negative voltage to positive one) polarization of the material will increase, respectively, there will be adsorption by the piezoelectric material of charge carriers isolated from the electrolyte solution. This process caused by piezoelectric properties will also lead to generation of highly active radicals ·OH or ·O2− in the medium. Thus, the principle of whitening effect of the piezoelectric material in conditions of periodic mechanical impact in an electrolyte medium is based on formation of reactive oxygen species causing oxidative cleavage of color pigments present on enamel. The effect is similar to photocatalytic reactions activated by the radiation. Experimental confirmation of described effects of piezoelectric materials is given in the study by Wang et al. [6]. It is shown that nanoparticles of barium titanate BaTiO3 (BTO) thanks to piezoelectric properties enable cleavage of organic colors. The results were obtained in experiments with a solution of indigo carmine used in the food industry as well as Rhodamine B under ultrasound impact imitating the teeth brushing process. Polarized samples of BTO lead to significant enamel tone lightening in case of vibration during 3 hours, removing staining caused by black tea, blueberry juice, wine and their combinations [6]. Analysis of micromorphological characteristics of teeth revealed that piezoelectric whitening is not mechanically destructive for tooth enamel. At the same time it was shown that treatment with 3% oxygen peroxide exerts more aggressive impact on enamel. The obtained data prove that with the use of piezoelectric materials formation of highly active radicals is significantly lower than with the use of 3% hydrogen peroxide, which prevents the risk of undesirable impact on enamel during whitening by the given method. Assessment of Vickers microhardness of tooth enamel did not reveal negative effects during treatment of teeth with piezoelectric materials. For BTO piezoelectric material nanoparticles no cytotoxic action was revealed in experiments for smooth muscle cells of A7r5 rats [6]. In the study by Wang et al. [6] it was confirmed that whitening is basically mediated