US-12622433-B2 - Bed bug control composition and process of preparing the same

US12622433B2US 12622433 B2US12622433 B2US 12622433B2US-12622433-B2

Abstract

The present invention provides a bed bug control composition comprising an azadirachtin extracted from neem seed kernels with a minimum purity 40% but not limited to the same, mixture of plant extracts and additives. The present invention provides a composition comprising azadirachtin, geraniol oil, citronella oil, Cedar wood oil, clove oil, rosemary oil, thyme oil and others. The present invention further provides a process for preparation of bed bug composition.

Inventors

Baburaj LAKSHMI KANTHAN
Kothapalli NARASIMHA RAO
Sambamoorthy BALAJI
Radhakrishnan Ramamurthi
Kathiresan SADHASIVAM
Chinaga SURESH KUMAR
Ponnusamy MANIMARAN
Govindasamy JAYABAL

Assignees

COROMANDEL INTERNATIONAL LTD.

Dates

Publication Date: 20260512
Application Date: 20200622
Priority Date: 20190624

Claims (6)

1 . A bed bug control composition comprising: an azadirachtin extract of a minimum percentage purity of 40% present in a range from 0.1% 80% (w/w); a mixture of plant extracts selected from the group consisting of: geraniol present in a range from 1% to 90% (w/w), citronella oil present in a range from 1% to 3% (w/w), clove oil present in a range from 1% to 5% (w/w), cedar wood oil present in a range from 1% to 2% (w/w), rosemary oil present in a range from 1% to 2% (w/w), thyme oil present in a range from 1% to 2% (w/w), eugenol present in a range from 1% to 5% (w/w), and peppermint oil in a range from 1% to 2% (w/w); and additives present in a range from 0.1% to 90% (w/w), wherein the additives consist of one or more solvents, one or more surfactants, and one or more emulsifiers, wherein the one or more solvents are selected from butyl acetate, ethyl acetate, or a combination thereof.
2 . The bed bug control composition as claimed in claim 1 , wherein the one or more surfactants are selected from the group consisting of ethoxylated alcohols, ethoxylated fatty esters, alkoxylated glycols, ethoxylated fatty acids, carboxylated alcohols, carboxylic acids, fatty acids, ethoxylated alkylphenols, fatty esters, sodium dodecylsulfide, fatty acid-based surfactants, natural surfactants, synthetic surfactants, and a combination thereof.
3 . The bed bug control composition as claimed in claim 1 , wherein the one or more emulsifiers are selected from silicone based emulsifiers, non-silicone based emulsifier, Olive oil, Cashew oil, Castor oil, Sunflower oil, Pongamia oil, Sesame oil, Linseed oil, Rice Bran oil, Ground nut oil, plant oils, animal oils, and combinations thereof.
4 . The bed bug control composition as claimed in claim 1 , wherein the composition is formulated in a form of a Ready to Use (RTU) or an Emulsified concentrate (EC).
5 . A process for preparation of the bed bug control composition of claim 1 , comprising the steps of: weighing the azadirachtin extracted from neem seed kernels in a predetermined amount, weighing the one or more solvents in a predetermined amount, adding the one or more solvents to the azadirachtin extracted from neem seed kernels with continuous stirring at 250 rpm for 30 minutes, adding the mixture of plant extracts in a predetermined amount, adding the one or more surfactants and the one or more emulsifiers with continuous stirring for 60 minutes.
6 . The process as claimed in claim 5 , wherein stirring is carried out at ambient temperature and pressure.

Description

CROSS-REFERENCE TO RELATED APPLICATIONS This application is a 371 U.S. National Stage of International Application No. PCT/IB2020/055851, filed Jun. 22, 2020, which claims priority to Indian Patent Application number 201841048984, filed Jun. 24, 2019. The disclosures of each of the above applications are incorporated herein by reference in their entirety. FIELD OF THE INVENTION The present invention relates to a bed bug control formulation. More particularly, the present invention relates to a bed bug control formulation comprising an azadirachtin extracted from neem seed kernels with a minimum purity 40% but not limited to the same, a mixture of plant extracts and additives. The present invention also relates to a process of preparing the bed bug control composition. BACKGROUND OF THE INVENTION Bed bugs are members of the genus Cimex. Cimex lectularius is commonly known bed bug as it prefers to feed on human blood. Other Cimex species are specialized to other animals e.g., bat bugs, Cimex pipistrelli, Cimex pilosellus and Cimex adjunctus. The name of the “bed bug” is derived from the preferred habitat of Cimex lectularius: warm houses, especially near or inside of beds, bedding, or other sleep areas. Bed bugs are tiny insects, ranging from 1-7 mm long and have a flat body shape enabling them to hide in narrow spaces, such as cracks and crevices. The control of bed bug is difficult. Bed bugs have a lifespan ranging from several months to up to four years and are able to go up to a year without a blood meal. Bed bugs are one of the most difficult pest problems to eradicate quickly. A number of insecticides have been proposed for killing bed bugs. These insecticides are effective in killing bedbugs but their toxicity towards non-targeted living organisms has been a major concern. Potent insecticides such as DDT (dichlorodiphenyltrichloroethane) to weaker insecticides such as pyrethroids have been used to control the bedbug nuisance. Drawbacks of these synthetic insecticides include development of resistance leading to reduced efficacy over time, carcinogenicity to humans and domestic animals, and other detrimental side effects. Also the current eradication strategies for bed bugs are costly, time consuming and often require a professional for implementation. In the field of insecticides and pesticides, as well as insect and pest repellents, much effort has been given to the development of compositions that are “environment friendly.” Accordingly, there has been a great interest in compositions that are readily biodegradable or otherwise compatible with human and animal for use as formulations having little or no toxicity. A limitation associated with developing these types of insecticides or pesticides is that they tend to be less effective and have short residual activity. The pesticides need to be developed with synergistic activity to make them as effective as the toxic chemicals with residual activity. Botanical insecticides are naturally occurring toxins extracted from plants. They are often less damaging to the environment than conventional synthetic or petroleum-based insecticides. To avoid chemical pesticides, a number of naturally occurring essential oils and their isolates have been evaluated for use as insect repellent. Most botanicals are rapid acting and most but not all botanicals are of low to moderate toxicity to mammals. Plants are considered as a rich source of bioactive chemicals and they may be an alternative source of bed bug killing agents. Natural products are generally preferred because of their less harmful nature to non-target organisms and due to their innate biodegradability. Existing natural bed bug killing formulations are not so effective. Azadirachtin is an extract from neem seed kernels of the neem tree. Neem tree is largely grown in India and is used as a commercial insect growth regulator that controls the metamorphosis method as the insect passes from the larva stage to the pupa stage. The Neem tree also yields extracts from its bark, leaves and wood that are used in medicine and cosmetics. Plant extract is an extract of a compound or multiple compounds from plant/herbs. The structure of plant/herbs is very complex and most of the ingredients are present in the form of organic compounds. However, the present invention shows synergistic effect of plant extracts used to kill bed bugs. The plant extracts includes, but not limited to azadirachtin, geraniol oil, Eucalyptus oil, citronella oil, Cedar wood oil, Eucalyptus oil, Pepper mint oil, Eugenol, Rosemary oil, Cinnamon oil, Clove oil, Geraniol, Garlic oil, Black pepper oil, Mint oil, Thyme oil, Basil oil, Camphor oil, Lemon grass oil, Henna oil, Cotton seed oil, Cedar leaf oil, Mustard oil, Corn oil, Marigold oil. Geraniol is a commercially available terpene alcohol that occurs in the essential oils of several aromatic plants. Geraniol is one of the most important molecules in the flavor. In addition to its pleasant odor, ge