US-12622651-B2 - Autoregulation status monitoring

US12622651B2US 12622651 B2US12622651 B2US 12622651B2US-12622651-B2

Abstract

Processing circuitry may receive one or more signals of a patient. The processing circuitry may determine an autoregulation status of the patient based at least in part on the one or more signals. The processing circuitry may output, for display at an output device, a graphical user interface (GUI) that includes an indication of the autoregulation status of the patient and an indication of a lower limit of autoregulation (LLA) value, wherein the GUI does not include an indication of an upper limit of autoregulation (LLA) value.

Inventors

Dean Montgomery
Paul S. Addison
Andre Antunes

Assignees

COVIDIEN LP

Dates

Publication Date: 20260512
Application Date: 20211029

Claims (14)

1 . A method comprising: receiving, by processing circuitry, a blood pressure signal comprising blood pressure values of a patient; determining, by the processing circuitry, an autoregulation status of the patient based at least in part on the blood pressure signal; displaying a graphical user interface (GUI) that includes a graph of the blood pressure values over time and an indication on the graph of the autoregulation status of the patient and an indication of a lower limit of autoregulation (LLA) at a first time, the LLA comprising a first blood pressure value below which autoregulation is impaired, wherein the autoregulation status of the patient on the graph includes a first graphical indication of a safe zone associated with an intact autoregulation state of the patient above the LLA and a second graphical indication of an unsafe zone associated with an impaired autoregulation state of the patient below the LLA; determining, by the processing circuitry, a change in the LLA at a second, subsequent time; and in response to determining the change in the LLA, updating the GUI, by the processing circuitry, wherein updating the GUI comprises visually changing: the indication of the LLA on the graph to an updated value of the LLA based on the change, and a portion of the first graphical indication of the safe zone that is prior to the change in the LLA, a portion of the second graphical indication of the unsafe zone that is prior to the change in the LLA, or both.
2 . The method of claim 1 , wherein: the safe zone is a first region of the GUI above the indication of the LLA; and the unsafe zone is a second region of the GUI below the indication of the LLA.
3 . The method of claim 1 , wherein the first graphical indication of the safe zone in the GUI is of a first color in the GUI, and wherein the second graphical indication of the unsafe zone in the GUI is of a second color different from the first color.
4 . The method of claim 1 , wherein updating the portion of the first graphical indication of the safe zone that is prior to the change in the LLA, the portion of the second graphical indication of the unsafe zone that is prior to the change in the LLA, or both comprises: updating, by the processing circuitry, the portion of the first graphical indication of the safe zone that is prior to the or change in the LLA, the portion of the second graphical indication of the unsafe zone that is prior to the change in the LLA, or both based at least in part on an amount of the change in the LLA.
5 . The method of claim 1 , wherein updating the portion of the first graphical indication of the safe zone that is prior to change in the LLA, the portion of the second graphical indication of the unsafe zone that is prior to the change in the LLA, or both comprises: updating, by the processing circuitry, a color of the portion of the first graphical indication of the safe zone that is prior to change in the LLA, a color of the portion of the second graphical indication of the unsafe zone that is prior to the change in the LLA, or both.
6 . The method of claim 1 , wherein updating the portion of the first graphical indication of the safe zone that is prior to the change in the LLA, the portion of the second graphical indication of the unsafe zone that is prior to the change in the LLA, or both comprises: updating, by the processing circuitry, a color intensity of the portion of the first graphical indication of the safe zone that is prior to the change in the LLA, a color intensity of the portion of the second graphical indication of the unsafe zone that is prior to the change in the LLA, or both.
7 . The method of claim 1 , wherein updating, by the processing circuitry, the indication of the LLA comprises adjusting the graphical indication of the LLA from a first position that corresponds to the first blood pressure value to a second position that corresponds to a second blood pressure value.
8 . The method of claim 1 , comprising: refraining, by the processing circuitry, from presenting an indication of an upper limit of autoregulation (ULA) comprising an upper blood pressure value above which autoregulation is impaired, such that the GUI does not include the indication of the ULA.
9 . The method of claim 8 , comprising refraining, by the processing circuitry, from presenting the indication of the ULA value in the GUI during a patient monitoring session, such that the GUI does not include the indication of the ULA during the patient monitoring session.
10 . A system comprising: a blood pressure sensor; and processing circuitry configured to: receive, from the blood pressure sensor, a blood pressure signal comprising blood pressure values of a patient; determine an autoregulation status of the patient based at least in part on the blood pressure signal; display a graphical user interface (GUI) that includes a graph of the blood pressure values over time and an indication on the graph of the autoregulation status of the patient and an indication of a lower limit of autoregulation (LLA) at a first time, the LLA comprising a blood pressure value below which autoregulation is impaired, wherein the autoregulation status of the patient on the graph includes a first graphical indication of a safe zone associated with an intact autoregulation state of the patient above the LLA and a second graphical indication of an unsafe zone associated with an impaired autoregulation state of the patient below the LLA; determine a change in the LLA at a second, subsequent time; and in response to determining the change in the LLA, update the indication of the LLA and update a portion of the first graphical indication of the safe zone that is prior to the change in the LLA, a portion of the second graphical indication of the unsafe zone that is prior to the change in the LLA, or both.
11 . The system of claim 10 , wherein the autoregulation status of the patient includes a first graphical indication of a safe zone associated with an intact autoregulation state of the patient and a second graphical indication of an unsafe zone associated with an impaired autoregulation state of the patient.
12 . The system of claim 11 , wherein: the safe zone is a first region of the GUI above the indication of the LLA; and the unsafe zone is a second region of the GUI below the indication of the LLA.
13 . The system of claim 10 , wherein the system includes the display.
14 . A non-transitory computer readable storage medium comprising instructions that, when executed, cause processing circuitry to: receive a blood pressure signal comprising blood pressure values of a patient; determine an autoregulation status of the patient based at least in part on the blood pressure signal; display a graphical user interface (GUI) that includes a graph of the blood pressure values over time and an indication on the graph of the autoregulation status of the patient and an indication of a lower limit of autoregulation (LLA) at a first time, the LLA comprising a first blood pressure value below which autoregulation is impaired, wherein the autoregulation status of the patient on the graph includes a first graphical indication of a safe zone associated with an intact autoregulation status of the patient above the LLA and a second graphical indication of an unsafe zone associated with an impaired autoregulation status of the patient below the LLA; determine a change in the LLA at a second, subsequent time; and in response to determining the change in the LLA, update the indication of the LLA and update a portion of the first graphical indication of the safe zone that is prior to the change in the LLA.

Description

This application is a continuation-in-part of U.S. patent application Ser. No. 16/204,061 entitled, “COMPENSATION FOR BLOOD PRESSURE SENSOR MOVEMENT” and filed on Nov. 29, 2018, the entire content of which is incorporated herein by reference. TECHNICAL FIELD This disclosure relates to monitoring autoregulation status of a patient. BACKGROUND Clinicians may monitor one or more physiological parameters of a patient, e.g., to monitor a patient's autoregulation status. Autoregulation is the response mechanism by which an organism regulates blood flow over a wide range of systemic blood pressure changes through complex myogenic, neurogenic, and metabolic mechanisms. During autoregulation, arterioles dilate or constrict in an attempt to maintain appropriate blood flow. Autoregulation may occur for a variety of organs and organ systems, such as, for example, the brain, the kidneys, the gastrointestinal tract, and the like. In the example of cerebral autoregulation, as cerebral blood pressure decreases, cerebral arterioles dilate in an attempt to maintain blood flow. As cerebral pressure increases, cerebral arterioles constrict to reduce the blood flow that could cause injury to the brain. SUMMARY This disclosure describes devices, systems, and techniques for monitoring a patient's autoregulation status by outputting, for display at a display device, a graphical user interface (GUI) that indicates the autoregulation (e.g., cerebral and/or non-cerebral) status value of a patient. When the patient exhibits an impaired autoregulation status, the patient may experience inappropriate blood flow, which may be undesirable. An autoregulation system of the patient may be impaired if the blood pressure gradient and the oxygen saturation gradient trend together (e.g., change in the same direction) over a period of time. An intact autoregulation status of the patient occurs over a range of blood pressures defined between a lower limit of autoregulation (LLA) and an upper limit of autoregulation (ULA). For example, below a lower limit of autoregulation (LLA), a drop in blood flow to a respective organ may cause ischemia and adversely affect the respective organ. A clinician may use the GUI to monitor the autoregulation status of a patient, e.g., during a medical procedure, and take one or more actions to keep the patient in or bring the patient to an intact autoregulation status, such as by increasing or decreasing the patient's blood pressure. While an indication of the LLA may be useful to clinicians monitoring the autoregulation status of the patient to determine whether the patient is in an intact autoregulation state or in an impaired autoregulation state by watching whether the blood pressure value of the patient, the ULA may not provide much useful information to the clinician. In fact, the ULA may distract clinicians from monitoring whether the patient is in an intact autoregulation state or in an impaired autoregulation state. As such, in accordance with aspects of the present disclosure, a monitoring device, such as a regional oximetry device, may output, for display at a display device, a GUI for monitoring the autoregulation status of the patient that does not include an indication of the ULA. Instead, the GUI may include information such as the blood pressure values of the patient over time, the autoregulation status of the patient over time, and the LLA (e.g., a patient-specific LLA). By not including an indication of the ULA in the GUI, the techniques of this disclosure may provide a GUI for monitoring the autoregulation status of a patient that is easier to use and less distracting to the clinician. For example, the GUI may be less cluttered with information because the GUI does not include an indication of the ULA, thereby allowing clinicians to focus on the LLA of the patient. Making the GUI that is easier to use and less distracting for the clinician may lead to better medical outcomes for the patient. In some aspects, a method includes receiving, by processing circuitry, one or more signals of a patient; determining, by the processing circuitry, an autoregulation status of the patient based at least in part on the one or more signals; and outputting, by the processing circuitry and for display at an output device, a graphical user interface (GUI) that includes an indication of the autoregulation status of the patient and an indication of a lower limit of autoregulation (LLA) value, wherein the GUI does not include an indication of an upper limit of autoregulation (ULA) value. In some aspects, a system includes one or more sensing devices; and processing circuitry configured to: receive, from the one or more sensing devices, one or more signals of a patient; determine an autoregulation status of the patient based at least in part on the one or more signals; and output, for display at an output device, a graphical user interface (GUI) that includes an indication of the autoregulation status of the patient and