US-12622745-B2 - Systems and methods for sealing cored or punctured tissue using inflatable balloon

US12622745B2US 12622745 B2US12622745 B2US 12622745B2US-12622745-B2

Abstract

Systems and methods for sealing tissue sites may comprise coring tissue at a target site such that a tissue core is removed from the target site thereby creating a core cavity at the target site and causing sealing of at least a portion of the target site.

Inventors

William Cohn
Terry Daglow
Matthew Kuhn
Steven Nguyen

Assignees

PRANA THORACIC, INC.

Dates

Publication Date: 20260512
Application Date: 20210315

Claims (20)

1 . A method for sealing tissue at a target site, the method comprising: anchoring a distal end of an anchor device to a portion of the target site; coring tissue at the target site to remove a section of cored tissue thereby creating a cored cavity; disposing, after removing the section of cored tissue, a sealing device across an opening of the cored cavity; causing at least a portion of the sealing device to seal across the opening of the cored cavity; delivering, after at least the portion of the cored cavity is sealed, a fill material to the target site, the fill material including autologous blood configured to clot after a predetermined period of time; holding the sealing device in place, via the anchor device, for the predetermined period of time to allow the autologous blood to clot at the target site; and spacing, after the predetermined period of time, the sealing device from the target site while leaving the fill material at the target site.
2 . The method of claim 1 , wherein the target site comprises tissue of a lung.
3 . The method of claim 1 , wherein the sealing device includes an inflatable balloon, and causing the portion of the sealing device to seal across the opening of the cored cavity includes inflating the inflatable balloon using a fluid.
4 . The method of claim 1 , wherein the sealing device includes an inflatable balloon, and causing the portion of the sealing device to seal across the opening of the cored cavity includes inflating the inflatable balloon to at least a radius of the cored cavity.
5 . The method of claim 1 , wherein the target site comprises at least a portion of a lung, the method further comprising causing the lung to collapse prior to disposing the sealing device across the opening of the cored cavity.
6 . The method of claim 1 , wherein the target site comprises at least a portion of a lung, the method further comprising allowing the lung to ventilate while the sealing device is sealing the opening of the cored cavity.
7 . The method of claim 1 , wherein a bio-adhesive is disposed on a surface of the sealing device such that the bio-adhesive contacts a wall of the cored cavity when the sealing device is caused to seal across the opening of the cored cavity.
8 . The method of claim 1 , wherein the sealing device is configured to deliver radiofrequency (RF) energy to at least a portion of a wall of the cored cavity.
9 . The method of claim 1 , wherein the sealing device includes an inflatable balloon, and causing the portion of the sealing device to seal across the opening of the cored cavity includes inflating the inflatable balloon, the method further comprising: deflating the inflatable balloon for removal from the cored cavity.
10 . A method for sealing tissue at a target site, the method comprising: disposing a port adjacent to tissue; anchoring a distal end of an anchor device to a portion of the target site; removing, using a tissue resection device, a section of cored tissue to create a cored tissue cavity; disposing, after removing the section of cored tissue, a sealing device through the port and adjacent to the cored tissue cavity while remaining outside of the cored tissue cavity; causing at least a portion of the sealing device to seal across an opening of the cored tissue cavity; delivering, after causing the portion of the sealing device to seal across the opening of the cored tissue cavity, a fill material to the target site, the fill material including autologous blood configured to clot after a predetermined period of time; and holding the sealing device in place, via the anchor device, for the predetermined period of time to allow the autologous blood to clot at the target site.
11 . The method of claim 10 , wherein the cored tissue cavity is formed in a lung.
12 . The method of claim 10 , wherein the sealing device includes an inflatable balloon, and causing the portion of the sealing device to seal across the opening of the cored tissue cavity includes inflating the inflatable balloon using a fluid.
13 . The method of claim 10 , wherein the sealing device includes an inflatable balloon, and causing the portion of the sealing device to seal across the opening of the cored tissue cavity includes inflating the inflatable balloon to at least radius of the cored tissue cavity.
14 . The method of claim 10 , wherein the cored tissue cavity is disposed in a lung, the method further comprising causing the lung to collapse prior to disposing the sealing device adjacent to the cored tissue cavity.
15 . The method of claim 10 , wherein the cored tissue cavity is disposed in a lung, the method further comprising allowing the lung to ventilate while the sealing device is sealing across the opening of the cored tissue cavity.
16 . The method of claim 10 , wherein the sealing device includes an inflatable balloon, and causing the portion of the sealing device to seal across the opening of the cored tissue cavity includes inflating the inflatable balloon, the method further comprising: deflating the inflatable balloon for removal from the cored tissue cavity.
17 . The method of claim 10 , further comprising removing the sealing device from the cored tissue cavity.
18 . A method for sealing tissue at a target site, the method comprising: anchoring a distal end of an anchor device to a portion of the target site; coring, using a coring device including a pair of electrodes, a tissue at a target site to remove a section of cored tissue thereby creating a cored cavity; disposing, after removing the coring device and the section of cored tissue, a sealing device adjacent to or within the cored cavity; causing at least a portion of the sealing device to abut a portion of the cored cavity to seal at least the portion of the cored cavity to form a sealed cavity; delivering, using a fill material delivery device, a fill material to the sealed cavity, the fill material including autologous blood configured to clot after a predetermined period of time; and holding the sealing device in place, via the anchor device, for the predetermined period of time to allow the autologous blood to clot at the target site.
19 . The method of claim 18 , wherein the target site comprises tissue of a lung.
20 . The method of claim 18 , wherein the sealing device includes an inflatable balloon, and causing the portion of the sealing device to seal at least the portion of the cored cavity includes inflating the inflatable balloon using a fluid.

Description

CROSS-REFERENCE TO RELATED APPLICATIONS This application claims priority to and the benefit of U.S. Patent Application No. 63/017,734 filed Apr. 30, 2020, which is hereby incorporated by reference in their entirety. BACKGROUND Tissue, such as lung tissue, may become punctured or may have a portion removed. Removal of tissue may include a surgery that involves coring and removal of a tissue specimen, for example, from the lung. However, problems may arise with cored or punctured tissue. Improvements are needed in managing cored or puncture tissue, such as lung tissue. SUMMARY It may be desirable to remove a core of tissue from target tissue sites including, but not limited to, the lungs, the liver, pancreas, or gastrointestinal (GI) tract, for which managing post-coring bleeding may be desired. A core of tissue may have a prescribed (e.g., pre-defined) shape (e.g., columnar) and dimension based on a coring apparatus. Such coring apparatus may be used to core the same or substantially the same shaped tissue core in a repeatable manner. Such coring may be distinguished from other tissue removal, for example using scissors or scalpel, where the cut tissue will not have a pre-defined shape or dimensions. Once cored, it may be desirable to seal the cored tissue. As described herein sealing may be desirable during a coring process, for example, to seal blood and/or fluid flow at the core site that may be caused from the coring operation itself. Additionally or alternatively, sealing may be desirable after a core of tissue and/or a coring device is removed. Moreover, sealing may occur at least once during a coring process and at least once after a core of tissue and/or a coring device is removed. As an illustrative example, the cored site may be sealed during a coring process to limit undesired blood or fluids from entering the cored site. Then, the cored site may be sealed after the tissue core is removed to limit undesired air to escape through the cored site, such as in the lungs. Various sealing operations may be used. Systems and/or methods for sealing tissue are described herein. A method for sealing tissue at a cored site may comprise coring tissue at a target site such that a tissue core is removed from the target site thereby creating a core cavity at the target site. A sealing device may be disposed adjacent the target site. The sealing device may be caused to seal at least a portion of the core cavity at the target site. The sealing device may be spaced (e.g., removed, separated, etc.) from the target site. Systems and/or methods for sealing tissue are described herein. An example method may comprise disposing a port to provide access to a target site. Example methods may comprise anchoring an anchor device, via the port, to a surface at the target site. Example methods may comprise disposing, via the port, a sealing device adjacent the target site. Example methods may comprise causing the sealing device to seal the target site. Example methods may comprise disposing a fill material adjacent the target site. The sealing device may minimize escape of the fill material from the target site. Systems and/or methods for sealing tissue are described herein. An example method may comprise disposing a sealing device adjacent a target site of a lung, while the lung is collapsed. Example methods may comprise causing the sealing device to seal the target site. Example methods may comprise disposing a fill material adjacent the target site. The sealing device may minimize escape of the fill material from the target site. Example methods may comprise spacing (e.g., removing, separating, etc.) the sealing device from the target site. Systems and/or methods for sealing tissue are described herein. An example method may comprise anchoring an anchor device to a surface at a target site. Example methods may comprise disposing, using the anchoring, a sealing device adjacent the target site. Example methods may comprise causing the sealing device to seal the target site. Example methods may comprise disposing a fill material adjacent the target site. The sealing device may minimize escape of the fill material from the target site. Systems and/or methods for sealing tissue are described herein. An example method may comprise disposing a fluid delivery device into a target site of a lung. Example methods may comprise disposing a fill material into the target site. Example methods may comprise spacing (e.g., removing, separating, etc.) the fluid delivery device from the target site. BRIEF DESCRIPTION OF THE DRAWINGS The following drawings show generally, by way of example, but not by way of limitation, various examples discussed in the present disclosure. In the drawings: FIG. 1 shows an application of an example system for sealing tissue. FIG. 2 shows an application of an example system for sealing tissue. FIG. 3 shows a flow diagram of an example method for sealing tissue. FIG. 4 shows a flow diagram of an example method for