US-12622866-B2 - Topical compositions and methods

Abstract

The present invention relates generally to methods of use and compositions useful for moisturizing skin and/or lightening or whitening skin. The composition includes a combination of Angelica acutiloba root extract and a Salicornia herbacea extract.

Inventors

• Greg Norman
• David Gan
• Michelle Hines
• Lisha VanPelt
• Wanli Zhao
• Barbara Durkee
• Lee Vickers
• Patricia Jacoby

Assignees

• MARY KAY INC.

Dates

Publication Date

20260512

Application Date

20230418

Claims (11)

1. 1 . A method of reducing inflammation in skin, the method comprising topically applying to skin in need thereof a composition comprising: Angelica acutiloba root extract; glycerin; dimethicone; butylene glycol; and ascorbyl glucoside wherein the skin is treated.
2. 2 . The method of claim 1 , wherein the composition further comprises squalene.
3. 3 . The method of claim 1 , wherein the composition further comprises: citric acid; hydrogenated coconut oil; hydrogenated lecithin; ethylparaben; methylparaben; and/or propylparaben.
4. 4 . The method of claim 1 , wherein the composition further comprises: mineral oil; petrolatum; dipotassium glycyrrhizate; and/or polysorbate 80.
5. 5 . The method of claim 1 , wherein the composition further comprises: sorbitan sesquioleate; cetyl ethylhexanoate; and/or cyclomethicone.
6. 6 . The method of claim 1 , wherein the composition further comprises Carthamus tinctorius (safflower) seed oil or Sesamum indicum (sesame) seed oil.
7. 7 . The method of claim 1 , wherein the topical composition is an emulsion, serum, gel, gel emulsion, gel serum, a cream, a cream-gel, a lotion, or a solution.
8. 8 . The method of claim 1 , wherein the composition further comprises cholesterol, cholesteryl hydroxystearate, and/or cholesterol esters.
9. 9 . The method of claim 1 , wherein the composition further comprises silica, botanical extracts, and/or ginseng extract.
10. 10 . The method of claim 1 , wherein the composition further comprises disodium EDTA, PEG-8, and/or water.
11. 11 . The method of claim 1 , wherein the composition further comprises tocopherol or tocopherol acetate.

Description

CROSS-REFERENCE TO RELATED APPLICATIONS The present application is a continuation of U.S. application Ser. No. 16/362,114 filed Mar. 22, 2019, which claims priority to U.S. Provisional Application Nos. 62/647,436 filed Mar. 23, 2018, and 62/799,528 filed Jan. 31, 2019. The disclosures of each application are hereby incorporated by reference in their entirety. BACKGROUND OF THE INVENTION A. Field of the Invention The present invention relates generally to topical skin compositions that can be used to clean, moisturize, lighten, whiten, and/or used to improve the skin's condition and/or visual appearance. The compositions include a combination of skin active ingredients to achieve these effects. This combination includes Angelica acutiloba root extract and Salicornia herbacea extract to the skin, which has been found to work particularly well in whitening skin, reducing skin inflammation, and increasing skin moisture. B. Description of Related Art Ageing, chronic exposure to adverse environmental factors, malnutrition, fatigue, etc., can change the visual appearance, physical properties, or physiological functions of skin and tissue in ways that are considered visually undesirable. The most notable and obvious changes include the development of fine lines and wrinkles, loss of elasticity, increased sagging, loss of firmness, loss of color evenness or tone, coarse surface texture, and mottled pigmentation. Less obvious but measurable changes which occur as skin and tissue ages or endures chronic environmental insult include a general reduction in cellular and tissue vitality, reduction in cell replication rates, reduced cutaneous blood flow, reduced moisture content, accumulated errors in structure and function, alterations in the normal regulation of common biochemical pathways, and a reduction in the skin's and tissue's ability to remodel and repair itself. Many of the alterations in appearance and function of the skin are caused by changes in the outer epidermal layer of the skin, while others are caused by changes in the lower dermis. The color in human skin is caused by the pigment melanin. Melanin is produced in special dendritic cells, melanocytes, which are found below or between the basal cells of the epidermis of the skin. When exposed to damaging environmental factors such the ultra violet (UV) radiation of the sun, irritants, and pollution, the keratinocyte (outermost cell of the skin) releases signaling molecules, such as α-melanocyte-stimulating hormone (α-MSH) and inflammatory cytokines, each of which can lead to unwanted skin pigmentation (e.g., hyperpigmented skin) and/or skin inflammation which is oftentimes characterized by reddened or erythemic skin, respectively. With respect to α-MSH, this hormone can trigger melanocytes to produce excess melanin, thereby producing unwanted skin pigmentation. Many individuals have excess melanin pigmentation or a hyperpigmentation patch, which can cause pigmentary variation or abnormal pigmentation of the skin. This can lead to unwanted freckles or dark spots such as senile lentigo, liver spots, melasma, brown or age spots, vitiligo, sunburn pigmentation, post-inflammatory hyperpigmentation due to abrasion, burns, wounds or dermatitis, phototoxic reaction and other similar small, fixed pigmented lesions. It is often desirable to lighten these areas or even out the appearance of irregularly pigmented areas of skin to provide a more even looking skin tone/skin color. Individuals may also wish to increase fairness or reduce the overall level of pigmentation in the skin. In either case, the hyperpigmentation is usually viewed as cosmetically undesirable and individuals often wish to lighten the skin. In some instances, the use of one skin lightening ingredient may not be effective for individuals with significant hyperpigmentation, freckles, or age spots, for example. Additionally, previous attempts to combine various skin lightening ingredients have been ineffective, and in some instance, have produced negative results such as exasperating the production of inflammatory cytokines. Furthermore, previous attempts to improve the visual appearance of skin with known skin active-ingredients have been shown to have various drawbacks such as skin irritation and prolonged recovery periods. Maintaining moisture of the skin can help overcome some unwanted changes in skin. However, maintaining moisture of the skin can be difficult (e.g., is more dry than average). Exposure to chemicals, solvents, washing, cosmetics, fabrics, or dry environments are some of the many ways that skin can lose moisture. Skin can lose moisture as a result of cleansing and/or freshening the skin. Skin cleansers and/or fresheners can be applied to skin and rinsed-off with water (e.g., rinse-off product), thereby, removing natural oils and lipids from the skin. Further, cleansers and/or fresheners oftentimes have ingredients that can be caustic to the skin. For instance, many types of cleansers