US-12623017-B2 - Activation mechanism for an on-body medicament delivery device

US12623017B2US 12623017 B2US12623017 B2US 12623017B2US-12623017-B2

Abstract

An activation mechanism for an on-body medicament delivery device, wherein the activation mechanism comprises: an activation button structure configured to be moved between an initial position and an activation position, an activation pin sleeve, and a biased activation pin received by the activation pin sleeve, the activation pin being configured to be linearly movable from an initial retracted position relative to the activation pin sleeve to an extended position towards which the activation pin is biased, the activation button structure being configured to interact with the activation pin sleeve in the initial position to cause the activation pin sleeve to engage with and maintain the activation pin in the retracted position, and wherein the activation button structure is configured to interact with the activation pin sleeve when the activation button structure is moved linearly towards the activation position causing the activation pin sleeve to release the activation pin from the retracted position.

Inventors

Daniel Scott
Slobodan Stefanov

Assignees

SHL MEDICAL AG

Dates

Publication Date: 20260512
Application Date: 20200408
Priority Date: 20190502

Claims (20)

1 . An activation mechanism for an on-body medicament delivery device, wherein the activation mechanism comprises: an activation button structure configured to be moved between an initial position and an activation position, an activation pin sleeve, and a biased activation pin received by the activation pin sleeve, the activation pin being configured to be linearly movable from a retracted position relative to the activation pin sleeve to an extended position towards which the activation pin is biased, the activation button structure being configured to interact with the activation pin sleeve in the initial position to cause the activation pin sleeve to engage with and maintain the activation pin in the retracted position, and wherein the activation button structure is configured to interact with the activation pin sleeve when the activation button structure is moved linearly towards the activation position causing the activation pin sleeve to disengage from the activation pin and release the activation pin from the retracted position.
2 . The activation mechanism as claimed in claim 1 , further comprising a biased delivery member mechanism which includes a delivery member, wherein when the delivery member mechanism is in a locked position, the delivery member is in an initial delivery member position, and the activation pin is in the retracted position, the activation pin is configured to be moved towards the extended position to release the delivery member mechanism from the locked position and thereby move the delivery member linearly from the initial delivery member position to an administration position.
3 . The activation mechanism as claimed in claim 2 , wherein the delivery member mechanism includes a torsionally biased first delivery member actuator and a linearly movable locking member configured to prevent rotation of the first delivery member actuator when the activation pin is in the retracted position whereby the delivery member mechanism is in the locked position, wherein the activation pin is configured to move the locking member and thereby release the first delivery member actuator when the activation pin is moved towards the extended position, causing the first delivery member actuator to rotate, whereby the delivery member mechanism is released from the locked position.
4 . The activation mechanism as claimed in claim 3 , wherein the delivery member mechanism includes a torsionally biased second delivery member actuator connected to the delivery member, wherein the first delivery member actuator is configured to apply a force onto the second delivery member actuator when the first delivery member actuator is rotated, thereby causing movement of the second delivery member actuator and movement of the delivery member to the administration position.
5 . The activation mechanism as claimed in claim 4 , wherein the second delivery member actuator is a delivery member actuating torsion spring having a leg connected to the delivery member, and wherein the first delivery member actuator is configured to apply the force onto the leg when the first delivery member actuator is rotated.
6 . The activation mechanism as claimed in claim 4 , wherein the second delivery member actuator forms a cam mechanism with the first delivery member actuator.
7 . The activation mechanism as claimed in claim 4 , wherein the delivery member mechanism comprises a drum containing a drum torsion spring, wherein the first delivery member actuator is a drum insert body arranged in the drum, torsionally biased by the drum torsion spring, wherein the drum insert body comprises a protrusion extending axially from the drum, the protrusion being configured to interact with the second delivery member actuator when the first delivery member actuator is rotated.
8 . The activation mechanism as claimed in claim 7 , wherein the first delivery member actuator is provided with a radial blocking protrusion configured to bear against the locking member in the retracted position of the activation pin to thereby prevent rotation of the first delivery member actuator.
9 . The activation mechanism as claimed in claim 8 , wherein the drum is provided with an axial slit in which the radial blocking protrusion is configured to run when moved by the activation pin.
10 . The activation mechanism as claimed in claim 1 , wherein the activation button structure comprises an activation button and an activation button sleeve fixedly connected to the activation button, wherein the activation button sleeve is configured to receive the activation pin sleeve, wherein the activation pin sleeve is provided with radially inwards extending flexible arms configured to engage with the activation pin, wherein the activation button sleeve is configured to force the radially inwards extending flexible arms radially inwards to engage with the activation pin when the activation button structure is in the initial position, and wherein the activation button sleeve is configured to move axially relative to the activation pin sleeve when the activation button structure is moved towards the activation position enabling the radially inwards extending flexible arms to flex radially outwards thereby releasing the activation pin from engagement with the activation pin sleeve.
11 . The activation mechanism as claimed in claim 1 , wherein the activation pin has an electrically conducting surface.
12 . An on-body medicament delivery device comprising: an outer housing, and the activation mechanism as claimed in claim 1 arranged in the outer housing, wherein the activation pin sleeve is fixed relative to the outer housing.
13 . The on-body medicament delivery device as claimed in claim 12 , comprising at least one electronic component and two contact elements that are spaced apart, wherein an electrically conducting surface of the activation pin is configured to provide an electrical connection between the two contact elements when the activation pin is in the extended position.
14 . The on-body medicament delivery device as claimed in claim 12 , comprising an inner housing provided with a first seal, wherein the activation pin is configured to pierce the first seal when the activation pin is moved from the retracted position towards the extended position.
15 . An activation mechanism for an on-body medicament delivery device, wherein the activation mechanism comprises: a button configured to allow a user to move the button between an initial position and an activation position; a button sleeve slidably connected to the button such that movement of the button linearly slides the button sleeve relative to a pin sleeve fixed in relation to an outer housing of the on-body medicament delivery device; and an activation pin linearly movable relative to the pin sleeve from a retracted position to an extended position, where a resilient member biases the activation pin when in the retracted position, wherein linear movement in a first direction of the button from the initial position to the activation position causes the resilient member to linearly move the activation pin in a second direction that is opposite of the first direction.
16 . The activation mechanism of claim 15 , wherein the pin sleeve releasably locks the activation pin to prevent linear movement of the activation pin when the button is in the initial position.
17 . The activation mechanism of claim 15 further comprising a delivery member configured to move tangentially relative to linear movement of the activation pin from an initial delivery member position to an administration position.
18 . The activation mechanism of claim 17 further comprising a torsionally biased delivery member actuator operatively connected to the delivery member causing movement from the initial delivery member position to the administration position.
19 . The activation mechanism of claim 17 , wherein the linear movement of the activation pin causes linear movement of a locking member that releases a torsionally biased delivery member actuator that is operatively connected to the delivery member.
20 . The activation mechanism of claim 15 , wherein the pin sleeve comprises a flexible arm that is biased radially inward by the button sleeve when the button is in the initial position.

Description

CROSS REFERENCE TO RELATED APPLICATIONS The present application is a U.S. National Phase Application pursuant to 35 U.S.C. § 371 of International Application No. PCT/EP2020/059964 filed Apr. 8, 2020, which claims priority to U.S. Provisional Patent Application No. 62/836,754 filed Apr. 22, 2019 and European Patent Application No. 19172201.6, filed May 2, 2019. The entire disclosure contents of these applications are herewith incorporated by reference into the present application. TECHNICAL FIELD The present disclosure generally relates to medicament deliver devices, in particular to on-body medicament delivery devices. BACKGROUND On-body medicament delivery devices, or wearable medicament delivery devices, is a category of devices that are worn by the user. On-body medicament delivery devices are hence configured to be fixed to the body of a user. They may for example be used when medicament administration should be performed over a timeframe that is longer than what an auto-injector or manual injector can provide. An on-body medicament delivery device may for example be configured to provide continuous medicament delivery for one or more hours. Since on-body medicament devices are worn by the user, the injection delivery member is typically contained within the on-body medicament delivery device before the injection sequence is commenced. The injection delivery member is typically inserted into the injection site after the user has triggered the injection sequence. WO2019/032384 A1 discloses a wearable injector which includes a housing, and an injection needle translatable along a needle axis between a retracted position in which the tip of the injection needle is contained within the injector housing, and an injection position in which the tip protrudes from the injector housing. An activation button structure is movably mounted to the injector housing and operatively connected to the injection needle. The activation button structure is translatable along a button axis, parallel to the needle axis, from an unactuated position to an actuated position which is visually different than the unactuated position. A biasing member is connected with the activation button structure and the injection needle. The biasing member is stabilized in a stored energy state in the unactuated position of the activation button structure and released in the actuated position of the activation button structure into an energy releasing state to drive the injection needle along the needle axis from the retracted position to the injection position. The configuration disclosed in WO2019/032384 A1 requires a design in which the needle is arranged is essentially arranged axially aligned with the button axis. Additionally, the design requires the depression of a biased button, which needs a high activation force. SUMMARY An object of the present disclosure is to provide an activation mechanism for an on-body medicament delivery device which solves or at least mitigates problems of the prior art. There is hence provided an activation mechanism for an on-body medicament delivery device, wherein the activation mechanism comprises: an activation button structure configured to be moved between an initial position and an activation position, an activation pin sleeve, and a biased activation pin received by the activation pin sleeve, the activation pin being configured to be linearly movable from an initial retracted position relative to the activation pin sleeve to an extended position towards which the activation pin is biased, the activation button structure being configured to interact with the activation pin sleeve in the initial position to cause the activation pin sleeve to engage with and maintain the activation pin in the retracted position, and wherein the activation button structure is configured to interact with the activation pin sleeve when the activation button structure is moved linearly towards the activation position causing the activation pin sleeve to release the activation pin from the retracted position. The pin sleeve can hence be translated along a longitudinal axis of the activation pin sleeve. This provides a freedom of design with regards to the location of the delivery member, e.g. a metal needle and/or a soft cannula. The activation button structure may be configured to be moved linearly between the initial position and the activation position. One embodiment comprises a biased delivery member mechanism, including a delivery member, which delivery member mechanism is in a locked position, in which the delivery member is in an initial delivery member position, when the activation pin is in the retracted position, wherein the activation pin is configured to release the delivery member mechanism from the locked position when the activation pin is moved towards the extended position to thereby move the delivery member linearly from the initial delivery member position to an administration position. The activation pin