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US-20260125617-A1 - TREATMENT FLUID FOR SOFT CONTACT LENS

US20260125617A1US 20260125617 A1US20260125617 A1US 20260125617A1US-20260125617-A1

Abstract

Provided is a treating solution for soft contact lenses capable of simply imparting hydrophilicity and lubricity to a soft contact lens surface, and excellent durability of such hydrophilicity and lubricity thereto. The treating solution for soft contact lenses of the present disclosure is achieved by dissolving a copolymer obtained by copolymerizing at least two specific kinds of monomers in a solvent at a specific concentration.

Inventors

  • Ryuya GOTANDA
  • Norio Iwakiri

Assignees

  • NOF CORPORATION

Dates

Publication Date
20260507
Application Date
20221024
Priority Date
20211029

Claims (11)

  1. 1 .- 3 . (canceled)
  2. 4 . A surface treatment method for a soft contact lens, the method including a step of bringing a solution for soft contact lenses into contact with a soft contact lens surface, wherein the solution for soft contact lenses contains 0.001 w/v % to 2.0 w/v % of a copolymer (P), the copolymer (P) having structural units represented by the following formulae (1a) and (1b), having a molar ratio n a :n b between the structural units of 10 to 90:10 to 90, and having a weight-average molecular weight of from 10,000 to 5,000,000: in the formula (1a) and the formula (1b), R 1 and R 2 each independently represent a hydrogen atom or a methyl group, and in the formula (1b), “n” represents from 4 to 90.
  3. 5 . The surface treatment method for a soft contact lens according to claim 4 , wherein the structural unit (1a) is 2-(methacryloyloxy)ethyl 2-(trimethylammonio)ethylphosphate.
  4. 6 . The surface treatment method for a soft contact lens according to claim 4 , wherein the copolymer (P) is a copolymer formed of the structural units represented by the formulae (1a) and (1b).
  5. 7 . The surface treatment method for a soft contact lens according to claim 5 , wherein the copolymer (P) is a copolymer formed of the structural units represented by the formulae (1a) and (1b).
  6. 8 . The surface treatment method for a soft contact lens according to claim 4 , wherein the structural unit (1a) is 2-(methacryloyloxy)ethyl 2-(trimethylammonio)ethylphosphate and the structural unit (1b) is methoxy polyethylene glycol methacrylate.
  7. 9 . A treating solution for soft contact lenses, comprising 0.001 w/v % to 2.0 w/v % of a copolymer (P), wherein the copolymer (P) has structural units represented by the following formulae (1a) and (1b), has a molar ratio n a :n b between the structural units of 10 to 90:10 to 90, and has a weight-average molecular weight of from 10,000 to 5,000,000: in the formula (1a) and the formula (1b), R 1 and R 2 each independently represent a hydrogen atom or a methyl group, and in the formula (1b), “n” represents from 4 to 90.
  8. 10 . The treating solution for soft contact lenses according to claim 9 , wherein the structural unit (1a) is 2-(methacryloyloxy)ethyl 2-(trimethylammonio)ethylphosphate.
  9. 11 . The treating solution for soft contact lenses according to claim 9 , wherein the copolymer (P) is a copolymer formed of the structural units represented by the formulae (1a) and (1b).
  10. 12 . The treating solution for soft contact lenses according to claim 10 , wherein the copolymer (P) is a copolymer formed of the structural units represented by the formulae (1a) and (1b).
  11. 13 . The treating solution for soft contact lenses according to claim 9 , wherein the structural unit (1a) is 2-(methacryloyloxy)ethyl 2-(trimethylammonio)ethylphosphate and the structural unit (1b) is methoxy polyethylene glycol methacrylate.

Description

TECHNICAL FIELD The present disclosure relates to a treating solution for soft contact lenses that can impart excellently sustained hydrophilicity and lubricity to a surface of a soft contact lens by simple treatment, and can provide a soft contact lens with sustained satisfactory wearing feeling lasting all day. The present application claims priority from Japanese Patent Application No. 2021-177580, which is incorporated herein by reference. BACKGROUND ART Hydrophilicity and lubricity of a surface of a soft contact lens are deeply involved in wearing feeling of the soft contact lens, and hence, in order to obtain a soft contact lens with sustained wearing feeling lasting all day, it is required that high hydrophilicity and lubricity of the surface of the lens be sustained for a long time period. In Patent Literature 1, there is a disclosure of a technology involving subjecting a soft contact lens to plasma treatment. In Patent Literature 2, there is a disclosure of a technology involving chemically bonding a soft contact lens having a reactive group and a hydrophilic polymer having a reactive group to each other to hydrophilize a surface of the soft contact lens. Each of the technologies of Patent Literature 1 and Patent Literature 2, which involves treating a soft contact lens itself to impart excellent hydrophilicity to a surface of the soft contact lens, provides excellent hydrophilicity and excellent durability thereof to the soft contact lens, but has room for improvement in lubricity of the soft contact lens. In addition, each of those technologies includes complicated surface treatment steps, and hence highly controlled production equipment is required, leading to an economic disadvantage in some cases. In each of Patent Literatures 3 and 4, there is a disclosure of a technology involving blending polyethylene glycol, a cellulose-based polymer, or the like into a treating solution for soft contact lenses to impart hydrophilicity to a soft contact lens surface and enhance hydrophilicity thereof, to thereby improve the wearing feeling. A phosphorylcholine-like group-containing polymer has a phospholipid-like structure derived from a biomembrane, and is known for having excellent characteristics, such as extremely high hydrophilicity and high moisture retention. The technology of Patent Literature 5 is a technology in which the wearing feeling is improved by adding a copolymer of a phosphorylcholine group-containing monomer and butyl methacrylate to a treating solution for soft contact lenses. CITATION LIST Patent Literature [PTL 1] WO 2010/092686 A1[PTL 2] WO 0001/074932 A1[PTL 3] WO 2009/032122 A1[PTL 4] WO 2012/098653 A1[PTL 5] US 2009/0100801 A1 SUMMARY OF INVENTION Technical Problem A contact lens using the treating solution for soft contact lenses described in each of Patent Literatures 3, 4, and 5 is excellent in wearing feeling, but adsorption of a copolymer to a contact lens surface is not sufficient, and hence improvement in the wearing feeling is temporary. An object of the present disclosure is to provide a treating solution for soft contact lenses capable of simply imparting hydrophilicity and lubricity to a soft contact lens surface, and excellent durability of such hydrophilicity and lubricity thereto. Solution to Problem The inventors of the present invention have made extensive investigations, and as a result, have found that the above-mentioned object can be achieved by dissolving a copolymer obtained by copolymerizing at least two specific kinds of monomers in a solvent at a specific concentration to provide an excellent treating solution for soft contact lenses. Thus, the inventors have completed the treating solution for soft contact lenses of the present disclosure. That is, a treating solution for soft contact lenses according to one embodiment of the present disclosure, a surface treatment method for a soft contact lens according to one embodiment of the present disclosure, and a use of a copolymer (P) for production of a treating solution for soft contact lenses according to one embodiment of the present disclosure are as described below. 1. A treating solution for soft contact lenses, including 0.001 w/v % to 2.0 w/v % of a copolymer (P), wherein the copolymer (P) has structural units represented by the following formulae (1a) and (1b), has a molar ratio na:nb between the structural units of 10 to 90:10 to 90, and has a weight-average molecular weight of from 10,000 to 5,000,000: in the formula (1a) and the formula (1b), R1 and R2 each independently represent a hydrogen atom or a methyl group, and in the formula (1b), “n” represents from 4 to 90. 2. The treating solution for soft contact lenses according to the above-mentioned item 1, wherein the structural unit (1a) is 2-(methacryloyloxy)ethyl 2-(trimethylammonio)ethylphosphate. 3. The treating solution for soft contact lenses according to the above-mentioned item 1 or 2, wherein the copolymer (P) is a copolymer formed of th