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US-20260125621-A1 - WATER-SOLUBLE UNIT DOSE ARTICLE COMPRISING A METALLOPROTEASE

US20260125621A1US 20260125621 A1US20260125621 A1US 20260125621A1US-20260125621-A1

Abstract

A water-soluble unit dose detergent article including a water-soluble film and a laundry liquid detergent composition, wherein the detergent composition includes: a non-soap surfactant system comprising anionic non-soap surfactant and nonionic surfactant wherein the anionic non-soap surfactant includes at least 80%, preferably at least 90% by weight of the anionic non-soap surfactant of linear alkyl benzene sulphonate; up to 15% by weight of the composition of water; a serine protease; a metalloprotease; and wherein the weight ratio of non-soap anionic surfactant to non-ionic surfactant is greater than 1.5:1.

Inventors

  • Karel Jozef Maria Depoot
  • Karolina Anna DRAPER
  • Nuray YALDIZKAYA

Assignees

  • THE PROCTER & GAMBLE COMPANY

Dates

Publication Date
20260507
Application Date
20250826
Priority Date
20240829

Claims (20)

  1. 1 . A water-soluble unit dose detergent article comprising a water-soluble film and a laundry liquid detergent composition, wherein the detergent composition comprises: a non-soap surfactant system comprising anionic non-soap surfactant and nonionic surfactant wherein the anionic non-soap surfactant comprises at least about 80%, by weight of the anionic non-soap surfactant of linear alkyl benzene sulphonate; up to about 15% by weight of the composition of water; a serine protease; a metalloprotease; and wherein the weight ratio of non-soap anionic surfactant to non-ionic surfactant is greater than 1.5:1.
  2. 2 . The detergent article according to claim 1 , wherein the anionic non-soap surfactant comprises at least about 95%, by weight of the anionic non-soap surfactant of linear alkyl benzene sulphonate.
  3. 3 . The detergent article according to claim 1 , wherein the anionic non-soap surfactant consists of linear alkyl benzene sulphonate.
  4. 4 . The detergent article according to claim 1 , wherein the detergent composition comprises from about 30% to about 65% by weight of the composition of the non-soap surfactant system.
  5. 5 . The detergent article according to claim 1 , wherein the anionic non-soap surfactant comprises less than about 1%, by weight of the anionic non-soap surfactant of alkyl sulphate and/or alkoxylated alkyl sulphate.
  6. 6 . The detergent article according to claim 1 , wherein the anionic non-soap surfactant is free of alkyl sulphate and/or alkoxylated alkyl sulphate anionic surfactant.
  7. 7 . The detergent article according to claim 1 , wherein the nonionic surfactant is selected from the group consisting of primary alcohol ethoxylate nonionic surfactant, secondary alcohol ethoxylate nonionic surfactant, and mixtures thereof.
  8. 8 . The detergent article according to claim 1 , wherein the detergent composition comprises from about 5% to about 30% by weight of the composition of organic solvent and wherein the organic solvent is selected from the group consisting of: 1,2-propanediol, dipropylene glycol, tripropyleneglycol, glycerol, sorbitol, polyethylene glycol, ethoxylated glycerine, or a mixture thereof.
  9. 9 . The detergent article according to claim 1 , wherein the weight ratio of non-soap anionic surfactant to non-ionic surfactant is from greater than about 1.5:1 to about 10:1, or from about 2:1 to about 5:1.
  10. 10 . The detergent article according to claim 1 , wherein the detergent composition further comprises a fatty acid, the detergent composition comprises between about 1.5% and about 20% by weight of the composition of the fatty acid.
  11. 11 . The detergent article according to claim 1 , wherein the metalloprotease is a metalloprotease selected from the M4, M7, M23 or M35 family.
  12. 12 . The detergent article according to claim 1 , wherein the metalloprotease is an M4 metalloprotease.
  13. 13 . The detergent article according to claim 1 , wherein the metalloprotease is a metalloprotease variant having a sequence identity of at least about 60% to the metalloprotease of SEQ ID NO:18 of WO2007/044993 with one or more mutations selected from the group consisting of S129I, S129V, S129L, F130L, M138I, M138L, V190I, V190L, D220E and D220P, one or more mutations selected from the group consisting of S129I, F130L, M138L, V190I and D220P.
  14. 14 . The detergent article according to claim 1 , wherein the metalloprotease is a metalloprotease variant having a sequence identity of at least about 80% to the metalloprotease of SEQ ID NO:18 of WO2007/044993 with one or more mutations selected from the group consisting of S129I, S129V, S129L, F130L, M138I, M138L, V190I, V190L, D220E and D220P.
  15. 15 . The detergent article according to claim 1 , wherein the metalloprotease is a metalloprotease variant having a sequence identity of at least about 90% to the metalloprotease of SEQ ID NO:18 of WO2007/044993 with one or more mutations selected from the group consisting of S129I, F130L, M138L, V190I and D220P.
  16. 16 . The detergent article according to claim 1 , wherein the metalloprotease is a metalloprotease variant having a sequence identity of at least about 60% to the metalloprotease of SEQ ID NO:33 of WO2014194034.
  17. 17 . The detergent article according to claim 1 , wherein the serine protease is a subtilase variant derived from B. amyloliquefaciens (BPN′) comprising at least one mutation in one or more of the following positions X003Q, X006W, X022Y, X024K, X024Q, X024G, X033T, X045V, X053G, X055P, S063T, X076D, X078N, X087D, X101N, X109Q, X118R, X128A, X128S, X145R, X166Q, X169A, X162Q, X182Q, X183N, S183T, X204Q, X206Y, X217Q, Y217L, X218S, X222Q, X248A or X254A (in BPN′ numbering system).
  18. 18 . The detergent article according to claim 1 , wherein the detergent composition further comprises an additional enzyme selected from the group consisting of proteases, amylase, cellulase, lipases, xyloglucanases, mannanases, nucleases, pectate lyases, and a mixture thereof.
  19. 19 . The detergent article according to claim 1 wherein the article comprises at least two compartments, a first compartment comprising the metalloprotease and a second compartment comprising the serine protease.
  20. 20 . The detergent article according to claim 1 , wherein the detergent composition further comprises an alkanolamine selected from the group comprising of monoethanolamine, diethanolamine, triethanolamine, and a mixture thereof.

Description

FIELD OF THE INVENTION Water-soluble unit dose article comprising a detergent composition comprising a surfactant system and a metalloprotease. REFERENCE TO AN ELECTRONIC SEQUENCE LISTING The contents of the electronic sequence listing (CM5754_SEQ_ID.xml; Size 23.4 KB (24.101 bytes)); and Date of Creation: Oct. 16, 2025 is hereby incorporated by reference in its entirety. BACKGROUND OF THE INVENTION Water-soluble unit dose detergent articles are liked by consumers as they are convenient and efficient to use. Such water-soluble unit dose articles comprise detergent compositions enveloped by a water-soluble film. When the water-soluble unit dose detergent article is added to water, the film dissolves/disintegrates releasing the detergent into the surrounding water to create a cleaning liquor. There are several reasons to formulate water-soluble unit dose articles comprising different detergent compositions, this can be dictated by the availability of raw material, the compatibility amongst the raw materials and of the raw materials with the water-soluble film etc. While formulating higher levels of anionic non-soap relative to nonionic surfactants typically favours greasy stain removal performance, such a formulation approach typically comes with a challenge towards enzyme sensitive stain removal performance. The water-soluble unit dose detergent article should be formulated in a way that delivers good overall cleaning, i.e., cleaning of different type of soils, such as both grease, sebum, and enzymatic sensitive stains including protein-based stain removal, whiteness, etc. Therefore, there is a need to provide a new water-soluble unit dose detergent article that provides good proteinaceous soil removal and good overall cleaning. SUMMARY OF THE INVENTION A water-soluble unit dose detergent article comprising a water-soluble film and a liquid detergent composition, wherein the detergent composition comprises: a non-soap surfactant system, the system comprising anionic non-soap surfactant and nonionic surfactant. The anionic non-soap surfactant comprises at least 80%, preferably at least 90% by weight of the anionic non-soap surfactant of linear alkyl benzene sulphonate;less than 15% by weight of the composition of water;a serine protease;a metalloprotease; andwherein the weight ratio of non-soap anionic surfactant to non-ionic surfactant is greater than 1.5:1. The detergent article provides good protein stain removal. DETAILED DESCRIPTION OF THE INVENTION Water-Soluble Unit Dose Article The present invention discloses a water-soluble unit dose article comprising a water-soluble film and a liquid detergent composition, preferably a liquid laundry detergent composition. The water-soluble film and the detergent composition are described in more detail below. The water-soluble unit dose detergent article comprises the water-soluble film shaped such that the unit-dose article comprises at least one internal compartment surrounded by the water-soluble film. The unit dose article may comprise a first water-soluble film and a second water-soluble film sealed to one another such to define the internal compartment. The water-soluble unit dose article is constructed such that the detergent composition does not leak out of the compartment during storage. However, upon addition of the water-soluble unit dose article to water, the water-soluble film dissolves and releases the contents of the internal compartment into the wash liquor. The compartment should be understood as meaning a closed internal space within the unit dose article, which holds the detergent composition. During manufacture, a first water-soluble film may be shaped to comprise an open compartment into which the detergent composition is added. A second water-soluble film is then laid over the first film in such an orientation as to close the opening of the compartment. The first and second films are then sealed together along a seal region. The unit dose article may comprise more than one compartment, even at least two compartments, or even at least three compartments, or even at least four compartments. The compartments may be arranged in superposed orientation, i.e. one positioned on top of the other. In such an orientation the unit dose article will comprise at least three films, top, one or more middle, and bottom. Alternatively, the compartments may be positioned in a side-by-side orientation, i.e. one orientated next to the other. The compartments may even be orientated in a ‘tyre and rim’ arrangement, i.e. a first compartment is positioned next to a second compartment, but the first compartment at least partially surrounds the second compartment but does not completely enclose the second compartment. Alternatively, one compartment may be completely enclosed within another compartment. Wherein the unit dose article comprises at least two compartments, one of the compartments may be smaller than the other compartment. Wherein the unit dose article compr