US-20260126427-A1 - BLOOD ANALYZER, BLOOD ANALYZING METHOD, AND PROGRAM

Abstract

A blood analyzer according to one or more embodiments may include: a specimen preparation part that prepares a measurement specimen by mixing a reagent into a blood preparation; a measurement part that measures the measurement specimen; a measurement mode selection unit that receives an input of a type of blood preparation as a measurement target selected from a plurality of types of blood preparations; and a controller. The controller may cause the specimen preparation part to prepare the measurement specimen depending on the selected type of blood preparation.

Inventors

• Osamu Kikuchi
• Takahito MIHARA
• Yuji Masuda
• Atsushi Shirakami
• Takuma Watanabe
• Daigo Fukuma
• Masaharu Shibata

Assignees

• SYSMEX CORPORATION

Dates

Publication Date

20260507

Application Date

20260102

Priority Date

20170810

Claims (20)

1. 1 . (canceled)
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17. 17 . A blood analyzer comprising: an aspirator comprising an aspiration tube, the aspirator configured to aspirate a sample by the aspiration tube; a specimen preparator comprising chambers respectively connected to a container containing a reagent, the specimen preparator configured to prepare measurement specimens in the chambers by mixing the reagent supplied from the container and the sample aspirated by the aspirator; a measurement part comprising an electrical resistance type detector, a hemoglobin detector configured to detect hemoglobin in the measurement specimen, and an optical detector, the measurement part configured to measure the measurement specimen, wherein the electrical resistance type detector comprises an aperture through which blood cells in one of the measurement specimens pass, the electrical resistance type detector configured to detect changes in electrical resistance while the blood cells pass through the aperture, and the optical detector comprises a flow cell in which the blood cells in other one of the measurement specimens flow, a light source configured to irradiate the blood cells flowing in the flow cell, and a light receiver configured to receive light from the blood cells flowing in the flow cell; and a controller comprising a processor, the controller configured to perform operations comprising: receiving a selection of a measurement mode among a plurality of measurement modes including a plurality of whole blood modes to measure a whole blood as the sample and a plurality of platelet preparation measurement modes to measure a platelet preparation as the sample, the plurality of platelet preparation modes including a first platelet preparation measurement mode and a second platelet preparation measurement mode; controlling the specimen preparator to prepare the measurement specimen depending on the received mode selection and controlling the measurement part to measure the prepared measurement specimen depending on the received mode selection; in response to a selection of the first platelet preparation measurement mode being received, controlling the specimen preparator and the measurement part to obtain a platelet count in the platelet preparation without obtaining a remaining white blood cell count in the platelet preparation; and in response to a selection of the second platelet preparation measurement mode being received, controlling the specimen preparator and the measurement part to obtain a platelet count and a remaining white blood cell count in the platelet preparation.
18. 18 . The blood analyzer of claim 17 , wherein the specimen preparator uses a common reagent in both the second platelet preparation measurement mode and at least one of the whole blood modes.
19. 19 . The blood analyzer of claim 18 , wherein the specimen preparator uses the common reagent to prepare a first measurement specimen as the measurement specimen in the second platelet preparation measurement mode, wherein the first measurement specimen is measured by the optical detector for remaining white blood cell count, and the specimen preparator uses the common reagent to prepare a second measurement specimen as the measurement specimen in at least one of the whole blood modes, wherein the second measurement specimen is measured by the optical detector for white blood cell measurement.
20. 20 . The blood analyzer of claim 17 , wherein the specimen preparator uses a common chamber among the chambers in both the second platelet preparation measurement mode and at least one of the whole blood modes.

Description

CROSS REFERENCE TO RELATED APPLICATIONS This application claims priority from prior Japanese Patent Application No. 2017-155938 filed with the Japan Patent Office on Aug. 10, 2017, the entire contents of which are incorporated herein by reference. BACKGROUND The present disclosure relates to a blood analyzer, a blood analyzing method, and a program. Blood preparations or blood products refer to pharmaceutical products including human blood or substances obtained from human blood as active ingredients. As the blood preparations, there are known component preparations prepared by separating components such as red blood cells, platelets, and plasma from human whole blood or human blood, and blood transfusions are now performed by mainly using the component preparations. The component preparations are used for blood component replacement therapies performed on patients undergoing various surgical operations, patients affected by blood diseases and cancers, and the like. It is known that, when a component preparation is transfused to a patient, white blood cells of a donor remaining in the perpetration cause blood transfusion reactions such as fever and allergic reactions and, in severe cases, cause blood transfusion reactions such as acute lung disorder. Accordingly, prestorage leukoreduction is performed on the component preparation to prevent the blood transfusion reactions. Moreover, since a certain percentage of white blood cells and red blood cells remain in the component preparation, sampling tests for the white blood cell count and red blood cell count are performed before the shipping of the preparation. Such sampling tests can be performed by using, for example, a flow system (general-purpose flow cytometer) described in Published Japanese Translation of PCT International Application No. 2011-521228 (Patent Literature 1). When a blood preparation is tested by using a general-purpose flow cytometer like one described above, in order to measure items necessary for blood preparation measurement, an operator needs to perform cumbersome procedures such as manually preparing a measurement specimen for each of the necessary items and individually setting a sensitivity of a detector, a blood cell fractionation method, and the like, before performing the measurement. In view of such a problem, one or more aspects may provide a blood analyzer, a blood analyzing method, and a program which enable smooth testing of a blood preparation. SUMMARY A blood analyzer according to one or more embodiments may include: a specimen preparation part that prepares a measurement specimen by mixing a reagent into a blood preparation; a measurement part that measures the measurement specimen; a measurement mode selection unit that receives an input of a type of blood preparation as a measurement target selected from a plurality of types of blood preparations; and a controller. The controller may cause the specimen preparation part to prepare the measurement specimen depending on the selected type of blood preparation. A blood analyzing method according to one or more embodiments may include: receiving a type of blood preparation selected from a plurality of types of blood preparation as a measurement target; preparing a measurement specimen based on the received type of blood preparation; and analyzing the prepared measurement specimen. A non-transitory computer-readable recording medium, according to one or more embodiments, storing a program causing a computer to perform operations may include: receiving a type of blood preparation selected from a plurality of types of blood preparations as a measurement target; preparing a measurement specimen depending on the received type of blood preparation; and analyzing the prepared measurement specimen. A blood analyzer according to one or more embodiments may include: a specimen preparation part that prepares a measurement specimen by mixing a reagent into a sample, a measurement part that measures the measurement specimen, and a measurement mode selection unit that receives, as a measurement target, an input of one of a blood preparation and whole blood. The specimen preparation part may prepare the measurement specimen depending on the received measurement target. BRIEF DESCRIPTION OF DRAWINGS FIG. 1 is a block diagram illustrating a configuration of a blood analyzer according to an embodiment 1; FIG. 2A is a perspective view illustrating a configuration of a container according to an embodiment 1, and FIG. 2B is a perspective view illustrating a configuration of a rack according to an embodiment 1; FIG. 3 is a diagram schematically illustrating configurations of a transport unit and a measurement unit according to an embodiment 1; FIG. 4A is a diagram schematically illustrating agitation of a container by an agitator according to an embodiment 1, and FIG. 4B is a table describing the numbers of times an agitator turns over a container according to an embodiment 1; FIG. 5 is a diagram