WO-2025083468-A8 - STRATIFICATION METHODS FOR ASSESSING THE PROGRESSION AND RISK OF ADVANCED ADENOMA AND COLORECTAL CANCER
WO2025083468A8WO 2025083468 A8WO2025083468 A8WO 2025083468A8WO-2025083468-A8
Abstract
The present disclosure concerns a computer-implemented method for transforming stool sample data into a diagnostic code, the method including: a) providing a stool sample from a subject; b) determining, as the stool sample data, expression levels of at least two distinct genes from a plurality of mRNA segments in the stool sample; and c) determining, by a computing system executing a machine-learning model and based on the stool sample data, a diagnostic code, wherein the machine-learning model was trained using stool diagnostic training data including a plurality of stool sample data labeled with at least one of two or more corresponding diagnostic codes.
Inventors
- EIDENS, MORITZ
- KRAMMES, Lena
- VON TÖRNE, Christian
Assignees
- MAINZ BIOMED N.V.
Dates
- Publication Date
- 20260507
- Application Date
- 20241016
- Priority Date
- 20231016